HitPredict

Interactor 1: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Interactor 2: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29402932, 24457600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0001701 - in utero embryonic development GO:0005634 - nucleus GO:0005654 - nucleoplasm and 2 others more... GO:0005829 - cytosol GO:0008270 - zinc ion binding
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 920 Hs			1 326
+	Hs
		487723 ANDR_HUMAN (1-920): 0: 966: 100.00		PCGF1_HUMAN (2-229): 5.96e-62: 199: 36.33
+	Hs
		487706 ANDR_HUMAN (1-920): 0: 966: 100.00		RING2_HUMAN (7-227): 8.37e-50: 170: 16.61
+	Hs
		282498 ANDR_HUMAN (1-920): 0: 966: 100.00		RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00
+	Hs
		414451 PRGR_HUMAN (469-920): 4.71e-106: 352: 45.73		BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00
+	Hs
		717519 HNF4A_HUMAN (536-906): 1e-104: 335: 22.85		BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00
+	Hs
		369497 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		TRI26_HUMAN (5-210): 1e-49: 175: 16.59
+	Hs
		1108525 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		PCGF3_HUMAN (4-228): 4.43e-72: 225: 34.03
+	Hs
		370271 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		RING2_HUMAN (7-227): 8.37e-50: 170: 16.61
+	Hs
		377629 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		RING2_HUMAN (7-227): 8.37e-50: 170: 16.61
+	Hs
		1019345 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		TRI26_HUMAN (5-210): 1e-49: 175: 16.59
+	Hs
		782645 HNF4A_HUMAN (536-906): 1e-104: 335: 22.85		PCGF1_HUMAN (2-229): 5.96e-62: 199: 36.33
+	Mm
		1142718 ERR2_MOUSE (467-904): 1.62e-109: 346: 23.64		RING2_MOUSE (7-227): 5.77e-50: 171: 16.61
+	Hs
		282522 RXRA_HUMAN (392-902): 7.05e-120: 374: 19.84		RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00
+	Hs
		782525 HNF4A_HUMAN (536-906): 1e-104: 335: 22.85		RING1_HUMAN (7-115): 2.38e-30: 120: 25.46