HitPredict

Interactor 1: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Interactor 2: MATK (P42679)
Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (CSK homologous kinase) (CHK) (Hematopoietic consensus tyrosine-lacking kinase) (Protein kinase HYL) (Tyrosine-protein kinase CTK)
Gene: MATK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	24728074
Identification Methods	pull down, fluorescence polarization spectroscopy
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0008284 - positive regulation of cell population proliferation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 920 Hs			1 507
+	Hs
		433225 ANDR_HUMAN (1-920): 0: 966: 100.00		YES_HUMAN (4-493): 0: 523: 31.94
+	Hs
		487088 ANDR_HUMAN (1-920): 0: 966: 100.00		SRC_HUMAN (30-493): 0: 523: 34.52
+	Hs
		454790 ANDR_HUMAN (1-920): 0: 966: 100.00		FGR_HUMAN (4-494): 0: 519: 32.03
+	Hs
		411564 ANDR_HUMAN (1-920): 0: 966: 100.00		LCK_HUMAN (39-492): 1.32e-180: 518: 34.62
+	Hs
		442764 ANDR_HUMAN (1-920): 0: 966: 100.00		HCK_HUMAN (26-490): 3.62e-178: 512: 33.47
+	Hs
		337320 ANDR_HUMAN (1-920): 0: 966: 100.00		ABL1_HUMAN (26-486): 1.44e-165: 499: 32.70
+	Hs
		487203 ANDR_HUMAN (1-920): 0: 966: 100.00		ABL2_HUMAN (13-503): 2.01e-164: 498: 31.37
+	Hs
		433537 ANDR_HUMAN (1-920): 0: 966: 100.00		LYN_HUMAN (14-490): 4.73e-171: 493: 31.73
+	Hs
		487245 ANDR_HUMAN (1-920): 0: 966: 100.00		BLK_HUMAN (10-492): 2.69e-169: 489: 32.66
+	Hs
		487415 ANDR_HUMAN (1-920): 0: 966: 100.00		PTK6_HUMAN (66-479): 8.11e-80: 258: 38.73
+	Hs
		368834 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		YES_HUMAN (4-493): 0: 523: 31.94
+	Hs
		368894 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		SRC_HUMAN (30-493): 0: 523: 34.52
+	Mm
		403414 ESR1_MOUSE (378-904): 2.5e-129: 403: 21.30		SRC_MOUSE (14-493): 0: 523: 34.07
+	Rn
		411266 ESR1_RAT (378-904): 2.19e-130: 406: 20.94		SRC_RAT (30-493): 0: 519: 34.52
+	Hs
		377007 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		FYN_HUMAN (28-493): 0: 527: 32.23
+	Hs
		377057 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		SRC_HUMAN (30-493): 0: 523: 34.52
+	Hs
		522762 RXRA_HUMAN (392-902): 7.05e-120: 374: 19.84		SRC_HUMAN (30-493): 0: 523: 34.52
+	Hs
		377006 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		LCK_HUMAN (39-492): 1.32e-180: 518: 34.62
+	Hs
		433435 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		YES_HUMAN (4-493): 0: 523: 31.94
+	Hs
		523091 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		SRC_HUMAN (30-493): 0: 523: 34.52