HitPredict

Interactor 1: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Interactor 2: UBP5 (P45974)
Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.4.19.12) (Deubiquitinating enzyme 5) (Isopeptidase T) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5)
Gene: USP5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35785414
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0008270 - zinc ion binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 920 Hs			1 858
+	Hs
		487848 ANDR_HUMAN (1-920): 0: 966: 100.00		UBP22_HUMAN (139-682): 5.21e-111: 352: 14.11
+	Hs
		487650 ANDR_HUMAN (1-920): 0: 966: 100.00		UBP7_HUMAN (247-777): 7.21e-80: 281: 13.17
+	Hs
		259262 ANDR_HUMAN (1-920): 0: 966: 100.00		UBP12_HUMAN (325-683): 3.4e-80: 264: 16.94
+	Hs
		271023 ANDR_HUMAN (1-920): 0: 966: 100.00		UBP2_HUMAN (700-854): 1.43e-11: 70.1: 16.05
+	Hs
		370605 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		UBP36_HUMAN (250-817): 9.73e-85: 295: 13.61
+	Hs
		370153 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		UBP7_HUMAN (247-777): 7.21e-80: 281: 13.17
+	Hs
		369123 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		UBP8_HUMAN (282-649): 3.4e-71: 256: 19.16
+	Hs
		377560 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		USP9X_HUMAN (289-758): 2.24e-84: 298: 16.20
+	Hs
		1269293 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		USP9X_HUMAN (289-758): 2.24e-84: 298: 16.20
+	Hs
		1269805 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		UBP36_HUMAN (250-817): 9.73e-85: 295: 13.61
+	Hs
		377377 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		UBP39_HUMAN (133-660): 1.38e-83: 280: 14.87
+	Hs
		1269294 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		UBP7_HUMAN (247-777): 7.21e-80: 281: 13.17
+	Hs
		1121181 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		UBP39_HUMAN (133-660): 1.38e-83: 280: 14.87
+	Hs
		377159 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		UBP8_HUMAN (282-649): 3.4e-71: 256: 19.16
+	Hs
		488004 RARA_HUMAN (460-902): 8.57e-110: 348: 19.87		UBP7_HUMAN (247-777): 7.21e-80: 281: 13.17
+	Mm
		59436 A3KN90_MOUSE (90-920): 4.3e-106: 353: 29.58		UBP2_MOUSE (241-660): 5.04e-72: 250: 15.70
+	Hs
		377422 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		UBP49_HUMAN (177-293): 1.05e-15: 83.7: 26.50
+	Hs
		1270054 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		UBP3_HUMAN (702-853): 3.54e-15: 81.2: 16.35
+	Hs
		271015 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		UBP2_HUMAN (700-854): 1.43e-11: 70.1: 16.05