HitPredict

Interactor 1: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Interactor 2: PRDX1 (Q06830)
Peroxiredoxin-1 (EC 1.11.1.24) (Natural killer cell-enhancing factor A) (NKEF-A) (Proliferation-associated gene protein) (PAG) (Thioredoxin peroxidase 2) (Thioredoxin-dependent peroxide reductase 2) (Thioredoxin-dependent peroxiredoxin 1)
Gene: PRDX1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	17909037
Identification Methods	anti bait coimmunoprecipitation, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 920 Hs			1 199
+	Hs
		487392 ANDR_HUMAN (1-920): 0: 966: 100.00		PRDX4_HUMAN (4-197): 4.03e-95: 279: 69.59
+	Hs
		369073 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		PRDX2_HUMAN (1-198): 2.38e-103: 297: 77.78
+	Hs
		369052 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		PRDX3_HUMAN (2-197): 1.85e-98: 287: 62.76
+	Hs
		369520 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		PRDX4_HUMAN (4-197): 4.03e-95: 279: 69.59
+	Rn
		415149 GCR_RAT (444-920): 1.59e-112: 365: 40.04		PRDX1_RAT (1-199): 1.37e-105: 303: 97.49
+	Hs
		377120 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		PRDX3_HUMAN (2-197): 1.85e-98: 287: 62.76
+	Hs
		685741 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		PRDX2_HUMAN (1-198): 2.38e-103: 297: 77.78
+	Hs
		414494 PRGR_HUMAN (469-920): 4.71e-106: 352: 45.73		PRDX1_HUMAN (1-199): 2.21e-105: 302: 100.00
+	Hs
		670988 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		PRDX3_HUMAN (2-197): 1.85e-98: 287: 62.76
+	Hs
		1026738 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		PRDX4_HUMAN (4-197): 4.03e-95: 279: 69.59
+	Hs
		369049 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		PRDX6_HUMAN (4-197): 5.84e-67: 206: 28.50
+	Hs
		611429 NR4A1_HUMAN (410-905): 1.85e-106: 343: 18.71		PRDX4_HUMAN (4-197): 4.03e-95: 279: 69.59
+	Hs
		670745 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		PRDX6_HUMAN (4-197): 5.84e-67: 206: 28.50
+	Hs
		487909 RARA_HUMAN (460-902): 8.57e-110: 348: 19.87		PRDX6_HUMAN (4-197): 5.84e-67: 206: 28.50
+	Hs
		611378 NR4A1_HUMAN (410-905): 1.85e-106: 343: 18.71		PRDX6_HUMAN (4-197): 5.84e-67: 206: 28.50
+	Hs
		670707 HNF4G_HUMAN (559-900): 2.71e-98: 315: 23.39		PRDX6_HUMAN (4-197): 5.84e-67: 206: 28.50