Interactor 1: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Interactor 2: NCOA4 (Q13772)
Nuclear receptor coactivator 4 (NCoA-4) (Androgen receptor coactivator 70 kDa protein) (70 kDa AR-activator) (70 kDa androgen receptor coactivator) (Androgen receptor-associated protein of 70 kDa) (Ret-activating protein ELE1)
Gene: NCOA4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.763

The method score is based on:

Property Details
Experiments 9636157, 11404460, 9892017, 10318905, 11818501, 10517667, 8643607, 17011702, 11779876, 12612084, 15604093, 10347167, 15563469
Identification Methods two hybrid, pull down, far western blotting, unspecified method, coimmunoprecipitation, biochemical, x-ray crystallography
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0008584 - male gonad development
GO:0030520 - estrogen receptor signaling pathway
GO:0071391 - cellular response to estrogen stimulus
GO:0071394 - cellular response to testosterone stimulus
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 920
Hs

1 614
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024