HitPredict

Interactor 1: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Interactor 2: KGP1 (Q13976)
cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent protein kinase I) (cGKI)
Gene: PRKG1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	23755100
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007165 - signal transduction
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 920 Hs			1 671
+	Hs
		487170 ANDR_HUMAN (1-920): 0: 966: 100.00		AKT1_HUMAN (243-666): 7.34e-152: 450: 29.66
+	Hs
		408536 ANDR_HUMAN (1-920): 0: 966: 100.00		KPCB_HUMAN (177-316): 2.87e-27: 119: 12.06
+	Hs
		487459 ANDR_HUMAN (1-920): 0: 966: 100.00		KS6A1_HUMAN (354-618): 2.6e-25: 113: 29.60
+	Hs
		369067 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		AKT2_HUMAN (243-663): 1.79e-154: 456: 29.41
+	Hs
		369066 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		AKT1_HUMAN (243-666): 7.34e-152: 450: 29.66
+	Hs
		368941 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		KAPCA_HUMAN (326-656): 6.58e-144: 424: 42.30
+	Hs
		377129 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		AKT1_HUMAN (243-666): 7.34e-152: 450: 29.66
+	Hs
		368873 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		KAP0_HUMAN (2-338): 8.18e-132: 395: 31.41
+	Hs
		622765 COT2_HUMAN (492-900): 2.13e-109: 345: 19.07		AKT2_HUMAN (243-663): 1.79e-154: 456: 29.41
+	Hs
		487911 RARA_HUMAN (460-902): 8.57e-110: 348: 19.87		AKT1_HUMAN (243-666): 7.34e-152: 450: 29.66
+	Hs
		622764 COT2_HUMAN (492-900): 2.13e-109: 345: 19.07		AKT1_HUMAN (243-666): 7.34e-152: 450: 29.66
+	Hs
		611379 NR4A1_HUMAN (410-905): 1.85e-106: 343: 18.71		AKT1_HUMAN (243-666): 7.34e-152: 450: 29.66
+	Hs
		616724 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		KS6B1_HUMAN (272-665): 4.14e-141: 423: 34.59
+	Hs
		1269834 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		KS6B2_HUMAN (333-665): 2.73e-140: 420: 38.17
+	Hs
		116957 MCR_HUMAN (401-920): 3.98e-106: 353: 38.18		SGK1_HUMAN (306-663): 5.41e-139: 415: 33.43
+	Hs
		568575 HNF4A_HUMAN (536-906): 1e-104: 335: 22.85		KAPCA_HUMAN (326-656): 6.58e-144: 424: 42.30
+	Hs
		217855 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		PRKY_HUMAN (346-583): 6.19e-67: 222: 44.54
+	Hs
		369662 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		KS6A1_HUMAN (354-618): 2.6e-25: 113: 29.60
+	Hs
		369218 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		KS6A3_HUMAN (360-603): 5.45e-24: 109: 30.47