HitPredict

Interactor 1: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Interactor 2: GRB7 (Q14451)
Growth factor receptor-bound protein 7 (B47) (Epidermal growth factor receptor GRB-7) (GRB7 adapter protein)
Gene: GRB7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	24728074
Identification Methods	pull down, fluorescence polarization spectroscopy
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 920 Hs			1 532
+	Hs
		487102 ANDR_HUMAN (1-920): 0: 966: 100.00		VAV_HUMAN (84-526): 4.42e-86: 285: 15.27
+	Hs
		487256 ANDR_HUMAN (1-920): 0: 966: 100.00		VAV2_HUMAN (81-526): 4.93e-78: 264: 14.77
+	Hs
		487829 ANDR_HUMAN (1-920): 0: 966: 100.00		VAV3_HUMAN (81-526): 1.65e-62: 221: 10.44
+	Hs
		411564 ANDR_HUMAN (1-920): 0: 966: 100.00		LCK_HUMAN (317-527): 2.74e-57: 200: 20.00
+	Hs
		487118 ANDR_HUMAN (1-920): 0: 966: 100.00		PLCG1_HUMAN (200-532): 6.64e-50: 187: 14.69
+	Hs
		487364 ANDR_HUMAN (1-920): 0: 966: 100.00		BTK_HUMAN (192-529): 1.31e-48: 180: 13.86
+	Hs
		433537 ANDR_HUMAN (1-920): 0: 966: 100.00		LYN_HUMAN (347-531): 4.7e-49: 178: 18.46
+	Hs
		454790 ANDR_HUMAN (1-920): 0: 966: 100.00		FGR_HUMAN (345-527): 5.44e-48: 176: 21.65
+	Hs
		433225 ANDR_HUMAN (1-920): 0: 966: 100.00		YES_HUMAN (366-528): 8.94e-48: 175: 19.53
+	Hs
		487088 ANDR_HUMAN (1-920): 0: 966: 100.00		SRC_HUMAN (351-528): 1.08e-46: 172: 24.32
+	Hs
		442764 ANDR_HUMAN (1-920): 0: 966: 100.00		HCK_HUMAN (349-527): 4.62e-45: 168: 19.37
+	Hs
		487202 ANDR_HUMAN (1-920): 0: 966: 100.00		MATK_HUMAN (398-525): 4.78e-36: 142: 30.37
+	Hs
		487209 ANDR_HUMAN (1-920): 0: 966: 100.00		KSYK_HUMAN (412-531): 6.62e-17: 86: 30.00
+	Hs
		487310 ANDR_HUMAN (1-920): 0: 966: 100.00		GRB2_HUMAN (427-513): 2.66e-13: 71: 29.89
+	Hs
		370679 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		VAV3_HUMAN (81-526): 1.65e-62: 221: 10.44
+	Hs
		368834 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		YES_HUMAN (366-528): 8.94e-48: 175: 19.53
+	Hs
		368894 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		SRC_HUMAN (351-528): 1.08e-46: 172: 24.32
+	Hs
		377006 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		LCK_HUMAN (317-527): 2.74e-57: 200: 20.00
+	Rn
		411266 ESR1_RAT (378-904): 2.19e-130: 406: 20.94		SRC_RAT (351-528): 1.16e-46: 172: 24.32
+	Mm
		403414 ESR1_MOUSE (378-904): 2.5e-129: 403: 21.30		SRC_MOUSE (351-528): 1.55e-46: 172: 24.32