HitPredict

Interactor 1: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Interactor 2: PAGR1 (Q9BTK6)
PAXIP1-associated glutamate-rich protein 1 (Glutamate-rich coactivator interacting with SRC1) (GAS) (PAXIP1-associated protein 1) (PTIP-associated protein 1)
Gene: PAGR1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	33640491, 23161582
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0033148 - positive regulation of intracellular estrogen receptor signaling pathway GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 920 Hs			1 254
+	Hs
		370333 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		PAGR1_HUMAN (1-254): 3.46e-131: 372: 100.00
+	Hs
		782646 HNF4A_HUMAN (536-906): 1e-104: 335: 22.85		PAGR1_HUMAN (1-254): 3.46e-131: 372: 100.00