HitPredict

Interactor 1: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Interactor 2: KDM5D (Q9BY66)
Lysine-specific demethylase 5D (EC 1.14.11.67) (Histocompatibility Y antigen) (H-Y) (Histone demethylase JARID1D) (Jumonji/ARID domain-containing protein 1D) (Protein SmcY) ([histone H3]-trimethyl-L-lysine(4) demethylase 5D)
Gene: KDM5D

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	27185910
Identification Methods	anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 920 Hs			1 1539
+	Hs
		487816 ANDR_HUMAN (1-920): 0: 966: 100.00		KDM5B_HUMAN (7-1523): 0: 1348: 45.20
+	Hs
		369044 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		KDM5A_HUMAN (6-1317): 0: 1176: 54.48
+	Hs
		377116 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		KDM5A_HUMAN (6-1317): 0: 1176: 54.48
+	Hs
		666545 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		KDM5A_HUMAN (6-1317): 0: 1176: 54.48
+	Hs
		487438 ANDR_HUMAN (1-920): 0: 966: 100.00		CHD4_HUMAN (257-936): 3.19e-116: 407: 13.28
+	Hs
		183054 ANDR_HUMAN (1-920): 0: 966: 100.00		KDM6A_HUMAN (353-758): 2.72e-82: 300: 15.51
+	Hs
		487518 ANDR_HUMAN (1-920): 0: 966: 100.00		KDM4D_HUMAN (337-675): 1.86e-84: 289: 27.58
+	Hs
		256937 ANDR_HUMAN (1-920): 0: 966: 100.00		KDM4A_HUMAN (337-655): 1.25e-78: 285: 27.05
+	Mm
		580484 ANDR_MOUSE (1-920): 0: 933: 84.30		KDM4C_MOUSE (337-655): 3.73e-77: 280: 26.75
+	Hs
		487382 ANDR_HUMAN (1-920): 0: 966: 100.00		CHD3_HUMAN (169-428): 4.57e-14: 80.1: 13.69
+	Hs
		369621 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		CHD4_HUMAN (257-936): 3.19e-116: 407: 13.28
+	Hs
		301117 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		KDM4B_HUMAN (337-655): 3.02e-79: 287: 26.44
+	Mm
		587106 ESR1_MOUSE (378-904): 2.5e-129: 403: 21.30		KDM4A_MOUSE (337-651): 5.48e-82: 295: 27.39
+	Mm
		587108 ESR1_MOUSE (378-904): 2.5e-129: 403: 21.30		KDM4B_MOUSE (337-654): 3.68e-79: 287: 26.52
+	Mm
		587107 ESR1_MOUSE (378-904): 2.5e-129: 403: 21.30		KDM4C_MOUSE (337-655): 3.73e-77: 280: 26.75
+	Hs
		150092 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		UTY_HUMAN (353-755): 1.52e-82: 300: 16.35
+	Hs
		183050 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		KDM6A_HUMAN (353-758): 2.72e-82: 300: 15.51
+	Hs
		183143 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		KDM6A_HUMAN (353-758): 2.72e-82: 300: 15.51
+	Hs
		301151 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		KDM4B_HUMAN (337-655): 3.02e-79: 287: 26.44
+	Hs
		370141 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		JARD2_HUMAN (11-324): 1.23e-43: 176: 19.21