HitPredict

Interactor 1: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Interactor 2: AFF4 (Q9UHB7)
AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31 protein) (Protein AF-5q31) (Major CDK9 elongation factor-associated protein)
Gene: AFF4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33640491
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 920 Hs			1 1163
+	Hs
		487431 ANDR_HUMAN (1-920): 0: 966: 100.00		MDC1_HUMAN (67-908): 1.82e-35: 149: 9.85
+	Hs
		487367 ANDR_HUMAN (1-920): 0: 966: 100.00		ZO1_HUMAN (80-902): 3.89e-34: 145: 12.83
+	Hs
		487803 ANDR_HUMAN (1-920): 0: 966: 100.00		CHD7_HUMAN (73-891): 6.5e-25: 115: 12.85
+	Mm
		580481 ANDR_MOUSE (1-920): 0: 933: 84.30		ATRX_MOUSE (45-862): 1.63e-31: 136: 12.95
+	Hs
		487522 ANDR_HUMAN (1-920): 0: 966: 100.00		NIPBL_HUMAN (91-887): 9.3e-18: 91.6: 16.10
+	Hs
		487596 ANDR_HUMAN (1-920): 0: 966: 100.00		KMT2C_HUMAN (263-920): 1.07e-09: 65.4: 9.56
+	Hs
		370646 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		AFF4_HUMAN (1-1163): 1.3e-124: 413: 100.00
+	Hs
		850823 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		AFF1_HUMAN (4-1160): 4.79e-88: 312: 34.47
+	Hs
		377487 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		AN36B_HUMAN (555-1125): 1.21e-59: 226: 10.33
+	Hs
		369607 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		MDC1_HUMAN (67-908): 1.82e-35: 149: 9.85
+	Mm
		101423 ESR1_MOUSE (378-904): 2.5e-129: 403: 21.30		F8VPR5_MOUSE (47-725): 5.12e-30: 132: 12.30
+	Hs
		370607 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		CHD7_HUMAN (73-891): 6.5e-25: 115: 12.85
+	Hs
		369815 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		NIPBL_HUMAN (91-887): 9.3e-18: 91.6: 16.10
+	Mm
		101427 RXRG_MOUSE (448-904): 6.52e-118: 369: 19.38		F8VPR5_MOUSE (47-725): 5.12e-30: 132: 12.30
+	Hs
		377760 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		CHD7_HUMAN (73-891): 6.5e-25: 115: 12.85
+	Hs
		370040 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		KMT2C_HUMAN (263-920): 1.07e-09: 65.4: 9.56
+	Hs
		377401 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		NIPBL_HUMAN (91-887): 9.3e-18: 91.6: 16.10
+	Hs
		517813 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		NFH_HUMAN (60-671): 4.82e-16: 85.7: 10.70
+	Hs
		311824 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		TACC2_HUMAN (32-1090): 5.83e-15: 82.4: 8.66
+	Hs
		231019 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		L37A3_HUMAN (45-623): 1.79e-10: 67.7: 8.62