Interactor 1: RARA (P10276)
Retinoic acid receptor alpha (RAR-alpha) (Nuclear receptor subfamily 1 group B member 1)
Gene: RARA

Interactor 2: RXRG (P48443)
Retinoic acid receptor RXR-gamma (Nuclear receptor subfamily 2 group B member 3) (Retinoid X receptor gamma)
Gene: RXRG

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.982

The method score is based on:

Property Details
Experiments 25910212, 25416956, 16189514, 21516116, 29892012, 32296183, 15604093, 21988832, 25303530, 31515488, unassigned1304, 20211142
Identification Methods two hybrid, pull down, two hybrid prey pooling approach, two hybrid array, validated two hybrid, two hybrid pooling approach, two hybrid bait and prey pooling approach
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Hormone_recep~Hormone_recep, Hormone_recep~zf-C4, zf-C4~zf-C4
Common GO terms GO:0000785 - chromatin
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0004879 - nuclear receptor activity
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 8 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 462
Hs

1 463
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Last updated: 15 Jul 2024