HitPredict

Interactor 1: RARA (P10276)
Retinoic acid receptor alpha (RAR-alpha) (Nuclear receptor subfamily 1 group B member 1)
Gene: RARA

Interactor 2: NCOA1 (Q15788)
Nuclear receptor coactivator 1 (NCoA-1) (EC 2.3.1.48) (Class E basic helix-loop-helix protein 74) (bHLHe74) (Protein Hin-2) (RIP160) (Renal carcinoma antigen NY-REN-52) (Steroid receptor coactivator 1) (SRC-1)
Gene: NCOA1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.980

The method score is based on:

Property Details
Experiments 17363140, 20338915, 10760302, 10082574, 17475621, 10454579, 9121466, 9192892, 23975195, 20543827, 16606617, 17641689, 16456540
Identification Methods pull down, affinity chromatography technology, fluorescent resonance energy transfer, two hybrid, x-ray crystallography, classical fluorescence spectroscopy, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Hormone_recep~SRC-1
Common GO terms GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 12 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Last updated: 15 Jul 2024