HitPredict

Interactor 1: RARA (P10276)
Retinoic acid receptor alpha (RAR-alpha) (Nuclear receptor subfamily 1 group B member 1)
Gene: RARA

Interactor 2: H2A1C (Q93077)
Histone H2A type 1-C (H2A-clustered histone 6) (Histone H2A/l)
Gene: H2AC6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30532072
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0008285 - negative regulation of cell population proliferation
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 462 Hs			1 130
+	Hs
		488015 RARA_HUMAN (1-424): 2.58e-148: 432: 100.00		H2A1A_HUMAN (1-130): 1.15e-66: 199: 93.89
+	Hs
		487991 RARA_HUMAN (1-424): 2.58e-148: 432: 100.00		H2A2B_HUMAN (1-130): 3.14e-66: 198: 95.39
+	Hs
		370295 ESR1_HUMAN (5-460): 2.32e-119: 362: 21.81		H2A1J_HUMAN (1-128): 5.32e-67: 200: 97.66
+	Hs
		369709 ESR1_HUMAN (5-460): 2.32e-119: 362: 21.81		H2A2C_HUMAN (1-130): 5.75e-65: 194: 96.92
+	Hs
		368928 ESR1_HUMAN (5-460): 2.32e-119: 362: 21.81		H2AX_HUMAN (1-130): 1.1e-63: 192: 89.55
+	Hs
		470485 ESR2_HUMAN (3-447): 3.53e-106: 327: 24.89		H2A1_HUMAN (1-130): 1.29e-67: 201: 98.46
+	Hs
		1269376 ESR2_HUMAN (3-447): 3.53e-106: 327: 24.89		H2A1H_HUMAN (1-128): 7.48e-67: 199: 98.44
+	Hs
		555566 ESR2_HUMAN (3-447): 3.53e-106: 327: 24.89		H2AX_HUMAN (1-130): 1.1e-63: 192: 89.55