HitPredict

Interactor 1: RARA (P10276)
Retinoic acid receptor alpha (RAR-alpha) (Nuclear receptor subfamily 1 group B member 1)
Gene: RARA

Interactor 2: AJUBA (Q96IF1)
LIM domain-containing protein ajuba
Gene: AJUBA

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	20133701
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005667 - transcription regulator complex and 2 others more... GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 462 Hs			1 538
+	Mm
		509338 RARA_MOUSE (1-462): 2.98e-150: 437: 98.27		AJUBA_MOUSE (1-538): 2.16e-95: 302: 91.79
+	Mm
		579896 RARG_MOUSE (1-456): 7.17e-133: 392: 70.81		AJUBA_MOUSE (1-538): 2.16e-95: 302: 91.79
+	Hs
		530807 RARG_HUMAN (1-448): 9.31e-131: 387: 71.62		AJUBA_HUMAN (1-538): 1.06e-96: 305: 100.00
+	Hs
		818884 RXRG_HUMAN (4-417): 9.54e-128: 380: 30.60		AJUBA_HUMAN (1-538): 1.06e-96: 305: 100.00
+	Hs
		369681 ESR1_HUMAN (5-460): 2.32e-119: 362: 21.81		TRIP6_HUMAN (80-530): 6.56e-57: 199: 25.81
+	Hs
		488030 RARA_HUMAN (1-424): 2.58e-148: 432: 100.00		LIMD1_HUMAN (14-536): 1.42e-19: 94.3: 14.99
+	Hs
		1076491 ESR2_HUMAN (3-447): 3.53e-106: 327: 24.89		TRIP6_HUMAN (80-530): 6.56e-57: 199: 25.81
+	Hs
		63202 RARA_HUMAN (1-424): 2.58e-148: 432: 100.00		WTIP_HUMAN (392-535): 6.42e-18: 88.2: 22.67
+	Mm
		926364 THA_MOUSE (88-392): 1.02e-64: 218: 37.46		AJUBA_MOUSE (1-538): 2.16e-95: 302: 91.79
+	Hs
		369590 ESR1_HUMAN (5-460): 2.32e-119: 362: 21.81		FHL2_HUMAN (364-537): 2.12e-34: 132: 22.16
+	Hs
		369176 ESR1_HUMAN (5-460): 2.32e-119: 362: 21.81		PAXI_HUMAN (19-459): 1.31e-29: 124: 18.72
+	Hs
		370509 ESR1_HUMAN (5-460): 2.32e-119: 362: 21.81		PDLI7_HUMAN (1-390): 1.99e-20: 95.9: 13.89
+	Hs
		1269355 ESR2_HUMAN (3-447): 3.53e-106: 327: 24.89		PDLI5_HUMAN (9-456): 1.16e-29: 125: 14.50
+	Hs
		823459 ESR2_HUMAN (3-447): 3.53e-106: 327: 24.89		PAXI_HUMAN (19-459): 1.31e-29: 124: 18.72
+	Hs
		1269706 ESR2_HUMAN (3-447): 3.53e-106: 327: 24.89		PDLI7_HUMAN (1-390): 1.99e-20: 95.9: 13.89
+	Hs
		1269848 ESR2_HUMAN (3-447): 3.53e-106: 327: 24.89		LIMD1_HUMAN (14-536): 1.42e-19: 94.3: 14.99
+	Hs
		500507 THB_HUMAN (14-416): 3.79e-103: 317: 32.17		PDLI7_HUMAN (1-390): 1.99e-20: 95.9: 13.89
+	Hs
		740536 PPARG_HUMAN (66-416): 9.52e-115: 348: 30.26		ZYX_HUMAN (22-391): 2.31e-09: 61.9: 16.83
+	Hs
		1269296 ESR2_HUMAN (3-447): 3.53e-106: 327: 24.89		LPP_HUMAN (10-454): 6.46e-11: 67: 13.00
+	Hs
		1080741 ESR2_HUMAN (3-447): 3.53e-106: 327: 24.89		ZYX_HUMAN (22-391): 2.31e-09: 61.9: 16.83