HitPredict

Interactor 1: RARA (P10276)
Retinoic acid receptor alpha (RAR-alpha) (Nuclear receptor subfamily 1 group B member 1)
Gene: RARA

Interactor 2: ITBP2 (Q9UKP3)
Integrin beta-1-binding protein 2 (Melusin)
Gene: ITGB1BP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.626

Property	Details
Experiments	15604093, 25036637
Identification Methods	two hybrid, affinity chromatography technology, luminescence based mammalian interactome mapping, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008270 - zinc ion binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 462 Hs			1 347
+	Hs
		500379 RARB_HUMAN (1-462): 6.17e-151: 438: 77.75		ITBP2_HUMAN (1-347): 4.03e-175: 491: 100.00
+	Hs
		530815 RARG_HUMAN (1-448): 9.31e-131: 387: 71.62		ITBP2_HUMAN (1-347): 4.03e-175: 491: 100.00
+	Hs
		1318125 Q9BZI0_HUMAN (238-337): 8.11e-60: 192: 91.00		ITBP2_HUMAN (1-347): 4.03e-175: 491: 100.00
+	Hs
		611530 NR4A1_HUMAN (16-420): 4.84e-105: 326: 30.50		SGT1_HUMAN (103-347): 3.34e-73: 232: 15.27
+	Hs
		73122 NR1H3_HUMAN (30-418): 6.46e-105: 320: 28.78		B4DYC6_HUMAN (150-347): 2.51e-57: 188: 16.32