HitPredict

Interactor 1: RARA (P10276)
Retinoic acid receptor alpha (RAR-alpha) (Nuclear receptor subfamily 1 group B member 1)
Gene: RARA

Interactor 2: TR150 (Q9Y2W1)
Thyroid hormone receptor-associated protein 3 (BCLAF1 and THRAP3 family member 2) (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150)
Gene: THRAP3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	25303530
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 462 Hs			1 955
+	Hs
		370764 ESR1_HUMAN (5-460): 2.32e-119: 362: 21.81		TR150_HUMAN (1-955): 9.81e-127: 408: 100.00
+	Hs
		370577 ESR1_HUMAN (5-460): 2.32e-119: 362: 21.81		BCLF1_HUMAN (38-949): 3.55e-78: 276: 33.19
+	Hs
		369909 ESR1_HUMAN (5-460): 2.32e-119: 362: 21.81		RBBP6_HUMAN (20-841): 1.66e-72: 264: 13.81
+	Hs
		1269775 ESR2_HUMAN (3-447): 3.53e-106: 327: 24.89		BCLF1_HUMAN (38-949): 3.55e-78: 276: 33.19
+	Hs
		1191700 ESR2_HUMAN (3-447): 3.53e-106: 327: 24.89		RBBP6_HUMAN (20-841): 1.66e-72: 264: 13.81
+	Hs
		370103 ESR1_HUMAN (5-460): 2.32e-119: 362: 21.81		ELYS_HUMAN (244-849): 8.04e-60: 226: 8.74
+	Hs
		1264560 ESR2_HUMAN (3-447): 3.53e-106: 327: 24.89		ELYS_HUMAN (244-849): 8.04e-60: 226: 8.74
+	Hs
		1035128 ESR2_HUMAN (3-447): 3.53e-106: 327: 24.89		MYO9B_HUMAN (113-540): 7.89e-44: 175: 13.03
+	Hs
		370728 ESR1_HUMAN (5-460): 2.32e-119: 362: 21.81		SRRM2_HUMAN (2-858): 2.43e-23: 109: 14.55
+	Mm
		581219 THB_MOUSE (50-416): 9.21e-119: 357: 35.12		NFH_MOUSE (2-547): 4.19e-21: 101: 11.72
+	Hs
		369607 ESR1_HUMAN (5-460): 2.32e-119: 362: 21.81		MDC1_HUMAN (2-649): 1.14e-11: 71.2: 8.49
+	Hs
		370105 ESR1_HUMAN (5-460): 2.32e-119: 362: 21.81		TITIN_HUMAN (105-799): 3.29e-11: 70: 7.20
+	Hs
		369815 ESR1_HUMAN (5-460): 2.32e-119: 362: 21.81		NIPBL_HUMAN (138-674): 7.25e-11: 68.9: 13.20
+	Hs
		782571 HNF4A_HUMAN (61-462): 6.66e-120: 360: 24.52		NIPBL_HUMAN (138-674): 7.25e-11: 68.9: 13.20
+	Hs
		517813 ESR2_HUMAN (3-447): 3.53e-106: 327: 24.89		NFH_HUMAN (335-886): 1.88e-16: 86.6: 12.97
+	Hs
		1056909 ESR2_HUMAN (3-447): 3.53e-106: 327: 24.89		MDC1_HUMAN (2-649): 1.14e-11: 71.2: 8.49
+	Hs
		1269843 ESR2_HUMAN (3-447): 3.53e-106: 327: 24.89		YM012_HUMAN (17-478): 1.19e-11: 70.4: 13.71
+	Hs
		1264774 ESR2_HUMAN (3-447): 3.53e-106: 327: 24.89		TITIN_HUMAN (105-799): 3.29e-11: 70: 7.20
+	Hs
		1154059 ESR2_HUMAN (3-447): 3.53e-106: 327: 24.89		NIPBL_HUMAN (138-674): 7.25e-11: 68.9: 13.20
+	Hs
		1186078 ESR2_HUMAN (3-447): 3.53e-106: 327: 24.89		MICA3_HUMAN (169-857): 2.66e-09: 63.4: 7.24