HitPredict

Interactor 1: RRAS (P10301)
Ras-related protein R-Ras (EC 3.6.5.-) (p23)
Gene: RRAS

Interactor 2: GDS1 (P52306)
Rap1 GTPase-GDP dissociation stimulator 1 (Exchange factor smgGDS) (SMG GDS protein) (SMG P21 stimulatory GDP/GTP exchange protein)
Gene: RAP1GDS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.858

Property	Details
Experiments	32296183, 33961781, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	Arm~Ras
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 218 Hs			1 607
+	Hs
		854086 RRAS2_HUMAN (42-218): 1.8e-88: 260: 66.85		GDS1_HUMAN (1-607): 0: 917: 100.00
+	Hs
		854133 RAB1B_HUMAN (22-215): 1.41e-79: 238: 30.69		GDS1_HUMAN (1-607): 0: 917: 100.00
+	Hs
		349206 RASH_HUMAN (42-217): 1.68e-56: 179: 53.41		GDS1_HUMAN (1-607): 0: 917: 100.00
+	Hs
		348587 RASN_HUMAN (42-218): 1.56e-55: 176: 51.98		GDS1_HUMAN (1-607): 0: 917: 100.00
+	Hs
		854082 RAP1B_HUMAN (30-208): 2.96e-55: 176: 50.00		GDS1_HUMAN (1-607): 0: 917: 100.00
+	Hs
		349994 RASK_HUMAN (42-213): 5.55e-54: 172: 51.74		GDS1_HUMAN (1-607): 0: 917: 100.00
+	Hs
		506444 RALB_HUMAN (30-197): 8.3e-54: 172: 50.89		GDS1_HUMAN (1-607): 0: 917: 100.00
+	Hs
		854088 RAP1A_HUMAN (30-192): 5.18e-54: 172: 51.83		GDS1_HUMAN (1-607): 0: 917: 100.00
+	Xl
		292764 RALBB_XENLA (30-197): 2.28e-54: 174: 51.48		GDS1A_XENLA (1-607): 0: 899: 85.50
+	Xl
		292765 RALBA_XENLA (30-197): 1.87e-54: 174: 50.89		GDS1A_XENLA (1-607): 0: 899: 85.50