Interactor 1: HLAC (P10321)
HLA class I histocompatibility antigen, C alpha chain (HLA-C) (HLA-Cw) (Human leukocyte antigen C)
Gene: HLA-C
Interactor 2: HFE (Q30201)
Hereditary hemochromatosis protein (HLA-H)
Gene: HFE
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.691 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 33961781 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | C1-set~C1-set, C1-set~MHC_I, MHC_I~MHC_I |
| Common GO terms | GO:0001916 - positive regulation of T cell mediated cytotoxicity GO:0002476 - antigen processing and presentation of endogenous peptide antigen via MHC class Ib GO:0002486 - antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent GO:0005102 - signaling receptor binding GO:0005615 - extracellular space and 2 others more... |
| Homologous interactions | 16 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
