HitPredict

Interactor 1: HLAC (P10321)
HLA class I histocompatibility antigen, C alpha chain (HLA-C) (HLA-Cw) (Human leukocyte antigen C)
Gene: HLA-C

Interactor 2: CLC4E (Q9ULY5)
C-type lectin domain family 4 member E (C-type lectin superfamily member 9) (Macrophage-inducible C-type lectin) (MINCLE)
Gene: CLEC4E

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.64 1.00 0.802

The method score is based on:

Property Details
Experiments 33961781, 34709727
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains C1-set~Lectin_C, Lectin_C~MHC_I
Common GO terms GO:0005886 - plasma membrane
GO:0009897 - external side of plasma membrane
GO:0016020 - membrane
GO:0030670 - phagocytic vesicle membrane
GO:0045087 - innate immune response
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 366
Hs

1 219
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024