HitPredict

Interactor 1: PRI1 (P10363)
DNA primase small subunit (EC 2.7.7.-) (DNA polymerase alpha:primase complex p48 subunit) (DNA polymerase-primase complex p48 subunit) (Pol alpha-primase complex p48 subunit) (DNA primase 48 kDa subunit)
Gene: PRI1

Interactor 2: DPOE (P21951)
DNA polymerase epsilon catalytic subunit A (EC 2.7.7.7) (3'-5' exodeoxyribonuclease) (EC 3.1.11.-) (DNA polymerase II subunit A)
Gene: POL2

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.674

Property	Details
Experiments	3888995, 2037567, 6376490
Identification Methods	affinity chromatography technology, coimmunoprecipitation, pull down, biochemical
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0043596 - nuclear replication fork
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 409 Sc			1 2222
+	Hs
		456100 PRI1_HUMAN (13-403): 0: 535: 30.62		DPOLA_HUMAN (89-635): 1.09e-97: 351: 12.42
+	Mm
		594817 PRI1_MOUSE (13-403): 0: 530: 31.25		DPOLA_MOUSE (89-635): 1.69e-98: 353: 11.62
+	Sc
		488477 PRI1_YEAST (1-409): 0: 570: 100.00		DPOLA_YEAST (231-637): 1.77e-77: 287: 10.92
+	Sp
		145029 PRI1_SCHPO (3-400): 0: 517: 41.94		DPOLA_SCHPO (213-636): 2.62e-73: 273: 12.88