Interactor 1: ARAF (P10398)
Serine/threonine-protein kinase A-Raf (EC 2.7.11.1) (Proto-oncogene A-Raf) (Proto-oncogene A-Raf-1) (Proto-oncogene Pks)
Gene: ARAF
Interactor 2: BRAF (P15056)
Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine sarcoma viral oncogene homolog B1)
Gene: BRAF
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 1.00 | 0.968 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 31980649, 34017080, 28514442, 28205554, 33961781, 17979178, 20130576, unassigned2173 |
| Identification Methods | affinity chromatography technology, fluorescent resonance energy transfer, anti bait coimmunoprecipitation, tandem affinity purification, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | C1_1~C1_1, C1_1~PK_Tyr_Ser-Thr, C1_1~RBD, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr, RBD~RBD |
| Common GO terms | GO:0000165 - MAPK cascade GO:0004672 - protein kinase activity GO:0004674 - protein serine/threonine kinase activity GO:0004709 - MAP kinase kinase kinase activity GO:0005524 - ATP binding and 6 others more... |
| Homologous interactions | 15 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
