HitPredict

Interactor 1: ARAF (P10398)
Serine/threonine-protein kinase A-Raf (EC 2.7.11.1) (Proto-oncogene A-Raf) (Proto-oncogene A-Raf-1) (Proto-oncogene Pks)
Gene: ARAF

Interactor 2: CDC37 (Q16543)
Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) [Cleaved into: Hsp90 co-chaperone Cdc37, N-terminally processed]
Gene: CDC37

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.752

The method score is based on:

Property Details
Experiments 29777862, 31980649, 35271311, 32707033, 24189400, 33961781, 25036637, unassigned2173
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 606
Hs

1 378
+ Hs
+ Hs
+ Hs
+ Mm
+ Gg
+ Rn
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024