HitPredict

Interactor 1: ARAF (P10398)
Serine/threonine-protein kinase A-Raf (EC 2.7.11.1) (Proto-oncogene A-Raf) (Proto-oncogene A-Raf-1) (Proto-oncogene Pks)
Gene: ARAF

Interactor 2: H90B3 (Q58FF7)
Putative heat shock protein HSP 90-beta-3 (Heat shock protein 90-beta c) (Heat shock protein 90Bc)
Gene: HSP90AB3P

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned2173
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 606 Hs			1 597
+	Hs
		542890 BRAF_HUMAN (3-604): 0: 546: 56.68		H90B3_HUMAN (1-597): 0: 838: 100.00
+	Hs
		437832 ARAF_HUMAN (1-606): 0: 579: 100.00		HS90B_HUMAN (1-597): 0: 799: 75.00
+	Hs
		431459 ARAF_HUMAN (1-606): 0: 579: 100.00		HS90A_HUMAN (1-597): 0: 798: 66.67
+	Hs
		374338 RAF1_HUMAN (13-606): 0: 534: 60.53		H90B3_HUMAN (1-597): 0: 838: 100.00
+	Hs
		432156 Q96II5_HUMAN (1-606): 0: 573: 99.51		HS90A_HUMAN (1-597): 0: 798: 66.67
+	Hs
		437860 BRAF_HUMAN (3-604): 0: 546: 56.68		HS90B_HUMAN (1-597): 0: 799: 75.00
+	Hs
		431496 BRAF_HUMAN (3-604): 0: 546: 56.68		HS90A_HUMAN (1-597): 0: 798: 66.67
+	Mm
		432406 BRAF_MOUSE (3-604): 0: 542: 55.81		HS90A_MOUSE (1-597): 0: 796: 65.76
+	Gg
		513713 BRAF_CHICK (3-604): 0: 542: 56.20		HS90A_CHICK (1-597): 0: 796: 66.16
+	Hs
		373549 RAF1_HUMAN (13-606): 0: 534: 60.53		HS90B_HUMAN (1-597): 0: 799: 75.00
+	Hs
		373543 RAF1_HUMAN (13-606): 0: 534: 60.53		HS90A_HUMAN (1-597): 0: 798: 66.67
+	Dm
		365432 KRAF1_DROME (5-605): 2.05e-167: 496: 42.18		HSP83_DROME (8-597): 0: 789: 60.67
+	Hs
		488555 ARAF_HUMAN (1-606): 0: 579: 100.00		ENPL_HUMAN (3-566): 0: 674: 37.68
+	Mm
		435915 BRAF_MOUSE (3-604): 0: 542: 55.81		ENPL_MOUSE (3-597): 0: 681: 36.34
+	Hs
		538082 BRAF_HUMAN (3-604): 0: 546: 56.68		ENPL_HUMAN (3-566): 0: 674: 37.68
+	Hs
		373626 RAF1_HUMAN (13-606): 0: 534: 60.53		ENPL_HUMAN (3-566): 0: 674: 37.68
+	Gg
		435893 BRAF_CHICK (3-604): 0: 542: 56.20		ENPL_CHICK (3-566): 0: 658: 37.39
+	Rn
		88624 D3ZHL1_RAT (50-606): 1.21e-128: 401: 25.66		HS90A_RAT (1-597): 0: 798: 66.17
+	Hs
		1162518 Q96II5_HUMAN (1-606): 0: 573: 99.51		Q6PK50_HUMAN (1-287): 6.7e-140: 411: 79.13
+	Hs
		374409 RAF1_HUMAN (13-606): 0: 534: 60.53		Q6PK50_HUMAN (1-287): 6.7e-140: 411: 79.13