HitPredict

Interactor 1: BCL2 (P10415)
Apoptosis regulator Bcl-2
Gene: BCL2

Interactor 2: BI1 (P55061)
Bax inhibitor 1 (BI-1) (Testis-enhanced gene transcript protein) (Transmembrane BAX inhibitor motif-containing protein 6)
Gene: TMBIM6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

The method score is based on:

Property	Details
Experiments	9660918, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0010523 - negative regulation of calcium ion transport into cytosol and 5 others more... GO:0016020 - membrane GO:0031625 - ubiquitin protein ligase binding GO:0032469 - endoplasmic reticulum calcium ion homeostasis GO:0043066 - negative regulation of apoptotic process GO:2001234 - negative regulation of apoptotic signaling pathway
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	239
Hs

1	237

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024