HitPredict

Interactor 1: BCL2 (P10415)
Apoptosis regulator Bcl-2
Gene: BCL2

Interactor 2: PP2AA (P67775)
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16) (Replication protein C) (RP-C)
Gene: PPP2CA

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 0.60 0.664

The method score is based on:

Property Details
Experiments 15225643, 9852076
Identification Methods enzymatic study, affinity chromatography technology, pull down, experimental interaction detection, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, dephosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0016020 - membrane
GO:0043029 - T cell homeostasis
and 1 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 239
Hs

1 309
+ Mm
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+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024