Interactor 1: BCL2 (P10415)
Apoptosis regulator Bcl-2
Gene: BCL2

Interactor 2: B2CL1 (Q07817)
Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X)
Gene: BCL2L1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.946

The method score is based on:

Property Details
Experiments 26186194, 28514442, 12137781, 33961781, 18835031, 14980220
Identification Methods affinity chromatography technology, unspecified method, pull down, anti tag coimmunoprecipitation, fluorescence polarization spectroscopy
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Bcl-2~Bcl-2, BH4~Bcl-2, BH4~BH4
Common GO terms GO:0001541 - ovarian follicle development
GO:0001836 - release of cytochrome c from mitochondria
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
and 22 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 239
Hs

1 233
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Last updated: 15 Jul 2024