Interactor 1: BCL2 (P10415)
Apoptosis regulator Bcl-2
Gene: BCL2
Interactor 2: BECN1 (Q14457)
Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197) [Cleaved into: Beclin-1-C 35 kDa; Beclin-1-C 37 kDa]
Gene: BECN1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.99 | 1.00 | 0.996 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16179260, 20622903, 25984893, 24599950, 29955058, 28431397, 23822101, 22082873, 28682313, 31696776, 9765397, 32097085, 32820146, 20889974, 21543763, 20010695, 21358617, 23564079, 21971985, 22622204 and 33 others
more... |
| Identification Methods | two hybrid, affinity chromatography technology, fluorescent resonance energy transfer, biochemical, pull down, anti tag coimmunoprecipitation, tandem affinity purification, anti bait coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | BH3~Bcl-2 |
| Common GO terms | GO:0005737 - cytoplasm GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol GO:0006915 - apoptotic process and 7 others more... |
| Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
