Interactor 1: MPPB (P10507)
Mitochondrial-processing peptidase subunit beta (EC 3.4.24.64) (Beta-MPP) (Mitochondrial assembly protein 1) (Processing enhancing protein) (PEP)
Gene: MAS1

Interactor 2: MPPA (P11914)
Mitochondrial-processing peptidase subunit alpha (Alpha-MPP) (Inactive zinc metalloprotease alpha) (Matrix processing peptidase) (MPP) (Mitochondrial assembly protein 2) (Mitochondrial import function protein 2)
Gene: MAS2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.954

The method score is based on:

Property Details
Experiments 2007593, 11805826, 16554755, 16429126, 37968396, 11470436
Identification Methods cross-linking study, tandem affinity purification, biochemical, affinity chromatography technology, x-ray crystallography
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Peptidase_M16~Peptidase_M16, Peptidase_M16~Peptidase_M16_C, Peptidase_M16_C~Peptidase_M16_C
Common GO terms GO:0004222 - metalloendopeptidase activity
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006627 - protein processing involved in protein targeting to mitochondrion
GO:0017087 - mitochondrial processing peptidase complex
and 1 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 462
Sc

1 482
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Ce
+ Dm
+ Sc
+ Hs
+ Hs
+ Sc
+ Sc

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Last updated: 15 Jul 2024