HitPredict

Interactor 1: PTPRF (P10586)
Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) (Leukocyte common antigen related) (LAR)
Gene: PTPRF

Interactor 2: PLAK (P14923)
Junction plakoglobin (Catenin gamma) (Desmoplakin III) (Desmoplakin-3)
Gene: JUP

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	9245795, 10187801
Identification Methods	pull down, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016477 - cell migration GO:0050839 - cell adhesion molecule binding GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1907 Hs			1 745
+	Hs
		489914 PTPRF_HUMAN (1-1907): 0: 1662: 100.00		CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38
+	Mm
		56908 PTPRF_MOUSE (1-1907): 0: 1662: 95.28		CTNB1_MOUSE (1-731): 2.79e-173: 518: 67.38
+	Rn
		1145481 PTPRF_RAT (1-1907): 0: 1652: 95.28		CTNB1_RAT (1-731): 1.13e-173: 519: 67.38
+	Hs
		576992 PTPRA_HUMAN (1136-1907): 0: 814: 40.13		CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38
+	Hs
		617080 PTPRG_HUMAN (909-1904): 0: 737: 27.21		CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38
+	Hs
		239047 PTPRA_HUMAN (1136-1907): 0: 814: 40.13		CTND1_HUMAN (203-728): 3.14e-90: 305: 16.25
+	Hs
		542300 PTPRJ_HUMAN (600-1904): 3.03e-141: 476: 18.11		PLAK_HUMAN (1-745): 0: 551: 100.00
+	Hs
		717036 PTPRJ_HUMAN (600-1904): 3.03e-141: 476: 18.11		CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38
+	Hs
		239120 PTPRJ_HUMAN (600-1904): 3.03e-141: 476: 18.11		CTND1_HUMAN (203-728): 3.14e-90: 305: 16.25
+	Hs
		617157 PTPRZ_HUMAN (1132-1623): 2.35e-47: 190: 19.69		CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38
+	Mm
		472765 PTPRQ_MOUSE (773-1388): 3.55e-30: 133: 15.27		PLAK_MOUSE (1-745): 0: 553: 98.39
+	Hs
		717247 PTPRU_HUMAN (238-855): 4.89e-31: 136: 14.44		CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38
+	Mm
		472764 PTPRQ_MOUSE (773-1388): 3.55e-30: 133: 15.27		CTNB1_MOUSE (1-731): 2.79e-173: 518: 67.38
+	Hs
		616904 PTPRB_HUMAN (502-1274): 6.16e-29: 129: 11.67		CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38
+	Dm
		578796 Q9W4F5_DROME (491-1328): 6.43e-38: 158: 13.31		ARM_DROME (2-730): 6.94e-161: 488: 60.33
+	Dm
		90970 E1JJE4_DROME (491-1328): 9.66e-38: 158: 13.31		ARM_DROME (2-730): 6.94e-161: 488: 60.33
+	Mm
		660881 PTPRM_MOUSE (105-534): 1.17e-17: 92.3: 14.22		CTNB1_MOUSE (1-731): 2.79e-173: 518: 67.38
+	Dm
		561758 PTP69_DROME (12-579): 2.1e-20: 101: 13.90		ARM_DROME (2-730): 6.94e-161: 488: 60.33
+	Mm
		472762 PTPRQ_MOUSE (773-1388): 3.55e-30: 133: 15.27		CTND1_MOUSE (207-730): 3.06e-94: 315: 16.42
+	Hs
		239058 PTPRM_HUMAN (105-534): 8.99e-17: 89.3: 14.22		CTND1_HUMAN (203-728): 3.14e-90: 305: 16.25