HitPredict

Interactor 1: SHOT1 (A0MZ66)
Shootin-1 (Shootin1)
Gene: SHTN1

Interactor 2: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	35271311, 36931259
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0045296 - cadherin binding GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 631 Hs			1 246
+	Hs
		49008 SHOT1_HUMAN (1-631): 0: 963: 100.00		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		49010 SHOT1_HUMAN (1-631): 0: 963: 100.00		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		48992 SHOT1_HUMAN (1-631): 0: 963: 100.00		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		49006 SHOT1_HUMAN (1-631): 0: 963: 100.00		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		49014 SHOT1_HUMAN (1-631): 0: 963: 100.00		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		48994 SHOT1_HUMAN (1-631): 0: 963: 100.00		1433S_HUMAN (3-239): 3.38e-100: 293: 68.62