HitPredict

Interactor 1: PTPRF (P10586)
Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) (Leukocyte common antigen related) (LAR)
Gene: PTPRF

Interactor 2: LIPA1 (Q13136)
Liprin-alpha-1 (LAR-interacting protein 1) (LIP-1) (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1)
Gene: PPFIA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.80	0.803

Property	Details
Experiments	8524829, 27880917, 7796809, 9624153
Identification Methods	two hybrid, proximity labelling technology, pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	SAM_1~Y_phosphatase
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1907 Hs			1 1202
+	Hs
		1025279 PTPRS_HUMAN (1-1907): 0: 1581: 65.73		LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00
+	Hs
		616970 PTPRD_HUMAN (29-1907): 0: 1573: 69.46		LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00
+	Hs
		259635 PTPRF_HUMAN (1-1907): 0: 1662: 100.00		LIPA2_HUMAN (35-1202): 3.45e-130: 431: 62.82
+	Hs
		259643 PTPRS_HUMAN (1-1907): 0: 1581: 65.73		LIPA2_HUMAN (35-1202): 3.45e-130: 431: 62.82
+	Hs
		259637 PTPRD_HUMAN (29-1907): 0: 1573: 69.46		LIPA2_HUMAN (35-1202): 3.45e-130: 431: 62.82
+	Hs
		255234 PTPRF_HUMAN (1-1907): 0: 1662: 100.00		LIPA3_HUMAN (1-265): 3.37e-12: 73.2: 12.45
+	Hs
		255244 PTPRS_HUMAN (1-1907): 0: 1581: 65.73		LIPA3_HUMAN (1-265): 3.37e-12: 73.2: 12.45
+	Hs
		255236 PTPRD_HUMAN (29-1907): 0: 1573: 69.46		LIPA3_HUMAN (1-265): 3.37e-12: 73.2: 12.45
+	Dm
		65322 LAR_DROME (1-1339): 1.18e-170: 573: 32.75		A8DYM0_DROME (860-1122): 3.71e-105: 360: 42.21
+	Dm
		114417 LAR_DROME (1-1339): 1.18e-170: 573: 32.75		M9PCD4_DROME (3-277): 4.35e-10: 66.3: 12.59
+	Dm
		561777 LAR_DROME (1-1339): 1.18e-170: 573: 32.75		Q9VM93_DROME (3-277): 1.13e-09: 65.1: 12.59