HitPredict

Interactor 1: PTPRF (P10586)
Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) (Leukocyte common antigen related) (LAR)
Gene: PTPRF

Interactor 2: I13R2 (Q14627)
Interleukin-13 receptor subunit alpha-2 (IL-13 receptor subunit alpha-2) (IL-13R subunit alpha-2) (IL-13R-alpha-2) (IL-13RA2) (Interleukin-13-binding protein) (CD antigen CD213a2)
Gene: IL13RA2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	IL6Ra-bind~fn3
Common GO terms	GO:0043235 - receptor complex
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1907 Hs			1 380
+	Hs
		1031984 PTPRS_HUMAN (1-1907): 0: 1581: 65.73		I13R2_HUMAN (1-380): 6.74e-94: 287: 100.00
+	Hs
		489957 PTPRF_HUMAN (1-1907): 0: 1662: 100.00		PTPRS_HUMAN (1-326): 1.04e-27: 117: 11.47
+	Hs
		616944 PTPRD_HUMAN (29-1907): 0: 1573: 69.46		EPHA8_HUMAN (18-355): 2.1e-58: 206: 14.16
+	Hs
		265768 PTPRS_HUMAN (1-1907): 0: 1581: 65.73		CRLF1_HUMAN (17-341): 1.33e-55: 190: 18.16
+	Hs
		616945 PTPRD_HUMAN (29-1907): 0: 1573: 69.46		IL2RG_HUMAN (116-372): 9.76e-50: 173: 22.47
+	Hs
		489886 PTPRF_HUMAN (1-1907): 0: 1662: 100.00		PTPRF_HUMAN (4-241): 4.11e-16: 82.5: 10.98
+	Hs
		616942 PTPRD_HUMAN (29-1907): 0: 1573: 69.46		IL3RA_HUMAN (98-372): 7.25e-44: 157: 19.31
+	Hs
		616971 PTPRS_HUMAN (1-1907): 0: 1581: 65.73		PTPRD_HUMAN (13-345): 1.32e-32: 131: 11.95
+	Hs
		616939 PTPRD_HUMAN (29-1907): 0: 1573: 69.46		PTPRD_HUMAN (13-345): 1.32e-32: 131: 11.95
+	Hs
		1031977 PTPRS_HUMAN (1-1907): 0: 1581: 65.73		PTPRS_HUMAN (1-326): 1.04e-27: 117: 11.47
+	Mm
		574008 PTPRA_MOUSE (1142-1907): 0: 799: 39.09		PTPRD_MOUSE (13-345): 7.93e-32: 129: 12.25
+	Mm
		69645 PTPRA_MOUSE (1142-1907): 0: 799: 39.09		PTPRS_MOUSE (4-344): 1.91e-24: 107: 11.14
+	Mm
		828098 PTPRE_MOUSE (1219-1907): 0: 771: 40.83		PTPRD_MOUSE (13-345): 7.93e-32: 129: 12.25
+	Mm
		56906 PTPRA_MOUSE (1142-1907): 0: 799: 39.09		PTPRF_MOUSE (4-274): 2.89e-17: 86: 10.04
+	Mm
		69646 PTPRE_MOUSE (1219-1907): 0: 771: 40.83		PTPRS_MOUSE (4-344): 1.91e-24: 107: 11.14
+	Hs
		581149 PTPRG_HUMAN (909-1904): 0: 737: 27.21		EPOR_HUMAN (129-343): 8.72e-32: 127: 16.17
+	Dm
		561767 LAR_DROME (1-1339): 1.18e-170: 573: 32.75		LAR_DROME (4-359): 2.69e-27: 116: 10.13
+	Hs
		500961 PTPRJ_HUMAN (600-1904): 3.03e-141: 476: 18.11		GHR_HUMAN (115-374): 1e-16: 83.7: 17.18