HitPredict

Interactor 1: PTPRF (P10586)
Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) (Leukocyte common antigen related) (LAR)
Gene: PTPRF

Interactor 2: MARH2 (Q9P0N8)
E3 ubiquitin-protein ligase MARCHF2 (EC 2.3.2.27) (Membrane-associated RING finger protein 2) (Membrane-associated RING-CH protein II) (MARCH-II) (RING finger protein 172) (RING-type E3 ubiquitin transferase MARCHF2)
Gene: MARCHF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	32614325, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1907 Hs			1 246
+	Hs
		489984 PTPRF_HUMAN (1-1907): 0: 1662: 100.00		MARH3_HUMAN (1-246): 2e-78: 238: 64.43
+	Hs
		489991 PTPRF_HUMAN (1-1907): 0: 1662: 100.00		MARH1_HUMAN (5-230): 1.5e-66: 209: 23.08
+	Hs
		489975 PTPRF_HUMAN (1-1907): 0: 1662: 100.00		MARH8_HUMAN (51-239): 1.91e-60: 193: 26.53
+	Hs
		617027 PTPRD_HUMAN (29-1907): 0: 1573: 69.46		MARH2_HUMAN (1-246): 2.21e-92: 273: 100.00
+	Hs
		1032007 PTPRS_HUMAN (1-1907): 0: 1581: 65.73		MARH1_HUMAN (5-230): 1.5e-66: 209: 23.08
+	Hs
		577045 PTPRA_HUMAN (1136-1907): 0: 814: 40.13		MARH1_HUMAN (5-230): 1.5e-66: 209: 23.08
+	Hs
		577071 PTPRA_HUMAN (1136-1907): 0: 814: 40.13		MARH4_HUMAN (50-212): 1.28e-46: 161: 22.56