HitPredict

Interactor 1: NR2F6 (P10588)
Nuclear receptor subfamily 2 group F member 6 (V-erbA-related protein 2) (EAR-2)
Gene: NR2F6

Interactor 2: NCOA1 (Q15788)
Nuclear receptor coactivator 1 (NCoA-1) (EC 2.3.1.48) (Class E basic helix-loop-helix protein 74) (bHLHe74) (Protein Hin-2) (RIP160) (Renal carcinoma antigen NY-REN-52) (Steroid receptor coactivator 1) (SRC-1)
Gene: NCOA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	10713182
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Hormone_recep~SRC-1
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 404 Hs			1 1441
+	Hs
		587177 RXRA_HUMAN (1-393): 1.77e-124: 369: 37.78		NCOA1_HUMAN (1-1441): 3.28e-155: 509: 100.00
+	Hs
		659718 RXRB_HUMAN (16-393): 5.95e-115: 347: 38.00		NCOA1_HUMAN (1-1441): 3.28e-155: 509: 100.00
+	Hs
		782555 HNF4A_HUMAN (31-397): 6.92e-112: 337: 36.51		NCOA1_HUMAN (1-1441): 3.28e-155: 509: 100.00
+	Hs
		914651 ERR3_HUMAN (12-393): 2.66e-109: 330: 28.24		NCOA1_HUMAN (1-1441): 3.28e-155: 509: 100.00
+	Hs
		126103 RXRA_HUMAN (1-393): 1.77e-124: 369: 37.78		BMAL1_HUMAN (1-539): 2.88e-105: 350: 16.16
+	Hs
		782560 HNF4A_HUMAN (31-397): 6.92e-112: 337: 36.51		HIF1A_HUMAN (8-798): 3.33e-103: 351: 13.33
+	Hs
		126108 HNF4A_HUMAN (31-397): 6.92e-112: 337: 36.51		BMAL1_HUMAN (1-539): 2.88e-105: 350: 16.16
+	Hs
		490089 COT1_HUMAN (1-404): 8.61e-138: 402: 58.76		AHR_HUMAN (2-833): 8.86e-80: 284: 13.86
+	Hs
		490120 COT1_HUMAN (1-404): 8.61e-138: 402: 58.76		NCOA3_HUMAN (1-1343): 5.25e-75: 277: 24.33
+	Mm
		914681 ERR3_MOUSE (12-393): 2.66e-109: 330: 28.24		EPAS1_MOUSE (15-890): 5.04e-96: 332: 13.94
+	Mm
		864788 ERR3_MOUSE (12-393): 2.66e-109: 330: 28.24		ARNT_MOUSE (4-656): 1.65e-93: 322: 16.20
+	Hs
		587212 RXRA_HUMAN (1-393): 1.77e-124: 369: 37.78		NCOA3_HUMAN (1-1343): 5.25e-75: 277: 24.33
+	Hs
		181498 RXRA_HUMAN (1-393): 1.77e-124: 369: 37.78		CLOCK_HUMAN (5-833): 1.42e-75: 271: 14.15
+	Hs
		782708 HNF4A_HUMAN (31-397): 6.92e-112: 337: 36.51		NCOA3_HUMAN (1-1343): 5.25e-75: 277: 24.33
+	Hs
		649056 HNF4A_HUMAN (31-397): 6.92e-112: 337: 36.51		ARNT_HUMAN (1-642): 5.73e-69: 250: 16.45
+	Hs
		490101 COT1_HUMAN (1-404): 8.61e-138: 402: 58.76		NCOA2_HUMAN (496-1439): 2.6e-11: 70.7: 9.43
+	Hs
		587173 RXRA_HUMAN (1-393): 1.77e-124: 369: 37.78		NCOA2_HUMAN (496-1439): 2.6e-11: 70.7: 9.43
+	Hs
		587195 RXRA_HUMAN (1-393): 1.77e-124: 369: 37.78		NPAS2_HUMAN (29-210): 2.08e-09: 64.3: 29.73
+	Mm
		587102 ESR1_MOUSE (56-390): 2.67e-112: 342: 25.28		NCOA2_MOUSE (496-1439): 7.26e-12: 72.6: 10.82
+	Hs
		782551 HNF4A_HUMAN (31-397): 6.92e-112: 337: 36.51		NCOA2_HUMAN (496-1439): 2.6e-11: 70.7: 9.43