HitPredict

Interactor 1: NR2F6 (P10588)
Nuclear receptor subfamily 2 group F member 6 (V-erbA-related protein 2) (EAR-2)
Gene: NR2F6

Interactor 2: C5AR2 (Q9P296)
C5a anaphylatoxin chemotactic receptor 2 (Complement component 5a receptor 2) (G-protein coupled receptor 77)
Gene: C5AR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 404 Hs			1 337
+	Hs
		490051 NR2F6_HUMAN (1-404): 5e-145: 419: 100.00		APJ_HUMAN (26-336): 6.02e-67: 216: 23.21
+	Hs
		622780 COT2_HUMAN (1-404): 1.45e-136: 398: 59.72		CXCR4_HUMAN (2-298): 9.99e-72: 228: 22.58
+	Hs
		622829 COT2_HUMAN (1-404): 1.45e-136: 398: 59.72		CML1_HUMAN (2-334): 1.35e-68: 220: 27.22
+	Hs
		622768 COT2_HUMAN (1-404): 1.45e-136: 398: 59.72		APJ_HUMAN (26-336): 6.02e-67: 216: 23.21
+	Hs
		622843 COT2_HUMAN (1-404): 1.45e-136: 398: 59.72		C5AR2_HUMAN (1-337): 1.47e-65: 211: 100.00
+	Hs
		369008 ESR1_HUMAN (10-390): 1.25e-98: 307: 23.97		ACKR3_HUMAN (8-307): 1.86e-75: 237: 21.47
+	Hs
		587124 RXRA_HUMAN (1-393): 1.77e-124: 369: 37.78		CXCR5_HUMAN (42-303): 8.88e-23: 99.4: 30.42
+	Hs
		487912 RARA_HUMAN (13-398): 1.34e-101: 310: 28.07		CXCR5_HUMAN (42-303): 8.88e-23: 99.4: 30.42