HitPredict

Interactor 1: COT1 (P10589)
COUP transcription factor 1 (COUP-TF1) (COUP transcription factor I) (COUP-TF I) (Nuclear receptor subfamily 2 group F member 1) (V-erbA-related protein 3) (EAR-3)
Gene: NR2F1

Interactor 2: FOXP1 (Q9H334)
Forkhead box protein P1 (Mac-1-regulated forkhead) (MFH)
Gene: FOXP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	29365100
Identification Methods	affinity chromatography technology, fluorescent resonance energy transfer
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:1990837 - sequence-specific double-stranded DNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 423 Hs			1 677
+	Hs
		622834 COT2_HUMAN (1-421): 1.77e-138: 404: 84.27		FOXP1_HUMAN (1-677): 0: 670: 100.00
+	Hs
		782655 HNF4A_HUMAN (27-414): 8.3e-117: 350: 31.96		FOXP1_HUMAN (1-677): 0: 670: 100.00
+	Hs
		178944 COT1_HUMAN (1-423): 1.76e-155: 447: 100.00		FOXP2_HUMAN (1-677): 0: 563: 60.19
+	Hs
		490105 COT1_HUMAN (1-423): 1.76e-155: 447: 100.00		FOXP4_HUMAN (1-666): 1.91e-179: 528: 55.22
+	Hs
		178947 COT2_HUMAN (1-421): 1.77e-138: 404: 84.27		FOXP2_HUMAN (1-677): 0: 563: 60.19
+	Hs
		622804 COT2_HUMAN (1-421): 1.77e-138: 404: 84.27		FOXP4_HUMAN (1-666): 1.91e-179: 528: 55.22
+	Hs
		175951 NR2F6_HUMAN (55-421): 1.39e-114: 342: 63.42		FOXN1_HUMAN (204-668): 1.99e-92: 301: 18.68
+	Hs
		490113 COT1_HUMAN (1-423): 1.76e-155: 447: 100.00		FOXC2_HUMAN (398-673): 7.83e-49: 180: 23.94
+	Hs
		490092 COT1_HUMAN (1-423): 1.76e-155: 447: 100.00		FOXA3_HUMAN (374-576): 2.44e-48: 175: 24.52
+	Hs
		490091 COT1_HUMAN (1-423): 1.76e-155: 447: 100.00		FOXG1_HUMAN (422-600): 2.95e-46: 173: 25.40
+	Hs
		490099 COT1_HUMAN (1-423): 1.76e-155: 447: 100.00		FOXL1_HUMAN (421-655): 3.8e-43: 160: 21.51
+	Hs
		622779 COT2_HUMAN (1-421): 1.77e-138: 404: 84.27		FOXA1_HUMAN (368-660): 2.83e-49: 181: 18.39
+	Hs
		782521 HNF4A_HUMAN (27-414): 8.3e-117: 350: 31.96		FOXK2_HUMAN (364-657): 1.47e-50: 188: 19.81
+	Hs
		487931 RARA_HUMAN (3-417): 3.02e-115: 346: 25.41		FOXA1_HUMAN (368-660): 2.83e-49: 181: 18.39
+	Hs
		369425 ESR1_HUMAN (7-423): 1.55e-104: 323: 23.25		FOXK2_HUMAN (364-657): 1.47e-50: 188: 19.81
+	Hs
		369258 ESR1_HUMAN (7-423): 1.55e-104: 323: 23.25		FOXA1_HUMAN (368-660): 2.83e-49: 181: 18.39
+	Hs
		369403 ESR1_HUMAN (7-423): 1.55e-104: 323: 23.25		FOXK1_HUMAN (367-650): 2.19e-44: 171: 22.77
+	Hs
		206786 ESR1_HUMAN (7-423): 1.55e-104: 323: 23.25		FOXO3_HUMAN (468-642): 3.42e-42: 164: 32.46
+	Hs
		377289 GCR_HUMAN (3-422): 2.13e-102: 322: 21.97		FOXL1_HUMAN (421-655): 3.8e-43: 160: 21.51
+	Hs
		377753 GCR_HUMAN (3-422): 2.13e-102: 322: 21.97		FOXJ2_HUMAN (465-546): 8.98e-13: 73.2: 42.22