HitPredict

Interactor 1: HSP71 (P10591)
Heat shock protein SSA1 (Heat shock protein YG100)
Gene: SSA1

Interactor 2: PSA2 (P23639)
Proteasome subunit alpha type-2 (Macropain subunit Y7) (Multicatalytic endopeptidase complex subunit Y7) (Proteasome component Y7) (Proteinase YSCE subunit 7)
Gene: PRE8

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	32868373, 19536198, 23217712
Identification Methods	affinity chromatography technology, tandem affinity purification, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 642 Sc			1 250
+	Dm
		505051 HSP7D_DROME (2-642): 0: 925: 73.15		PSA2_DROME (2-250): 2.44e-105: 306: 53.41
+	Hs
		503490 HSP7C_HUMAN (2-642): 0: 937: 73.91		PSA5_HUMAN (3-250): 9.42e-92: 272: 30.04
+	Hs
		503469 HSP7C_HUMAN (2-642): 0: 937: 73.91		PSA4_HUMAN (1-247): 4.63e-91: 270: 34.40
+	Hs
		503791 HSP7C_HUMAN (2-642): 0: 937: 73.91		PSA6_HUMAN (2-250): 4.86e-91: 270: 32.54
+	Hs
		156208 HSP7C_HUMAN (2-642): 0: 937: 73.91		PSA7_HUMAN (1-248): 8.69e-90: 267: 32.00
+	Hs
		503467 HSP7C_HUMAN (2-642): 0: 937: 73.91		PSA2_HUMAN (1-250): 3.12e-90: 267: 56.97
+	Sc
		493244 HSP72_YEAST (1-642): 0: 922: 96.26		PSA2_YEAST (1-250): 4.68e-95: 280: 100.00
+	Sc
		490393 HSP71_YEAST (1-642): 0: 925: 100.00		PSA3_YEAST (4-214): 4.62e-42: 145: 37.09