HitPredict

Interactor 1: HSP71 (P10591)
Heat shock protein SSA1 (Heat shock protein YG100)
Gene: SSA1

Interactor 2: MSP1 (P28737)
Outer mitochondrial transmembrane helix translocase (EC 7.4.2.-) (Mitochondrial sorting of proteins) (Tat-binding homolog 4)
Gene: MSP1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.660

Property	Details
Experiments	35876647, 22940862, 16429126
Identification Methods	pull down, affinity chromatography technology, tandem affinity purification
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0006626 - protein targeting to mitochondrion GO:0016887 - ATP hydrolysis activity
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 642 Sc			1 362
+	Hs
		503623 HSP7C_HUMAN (2-642): 0: 937: 73.91		PRS6B_HUMAN (7-312): 1.63e-104: 315: 31.83
+	Hs
		66342 Q53FC7_HUMAN (4-642): 0: 937: 69.32		A8K2M0_HUMAN (7-312): 1.63e-104: 315: 31.83
+	Sc
		493376 HSP72_YEAST (1-642): 0: 922: 96.26		MSP1_YEAST (1-362): 8.22e-107: 319: 100.00
+	Sc
		450155 HSP73_YEAST (1-642): 0: 925: 79.05		PRS8_YEAST (5-333): 9.57e-105: 315: 27.81
+	Sc
		492161 HSP71_YEAST (1-642): 0: 925: 100.00		PRS8_YEAST (5-333): 9.57e-105: 315: 27.81
+	Sc
		494737 HSP72_YEAST (1-642): 0: 922: 96.26		PRS8_YEAST (5-333): 9.57e-105: 315: 27.81
+	Rn
		926183 HSP7C_RAT (2-642): 0: 937: 74.07		KTNA1_RAT (31-361): 3.58e-96: 296: 30.26
+	Hs
		503834 HSP7C_HUMAN (2-642): 0: 937: 73.91		PRS10_HUMAN (5-342): 8.41e-97: 294: 29.16
+	Hs
		503823 HSP7C_HUMAN (2-642): 0: 937: 73.91		PRS8_HUMAN (5-336): 2.62e-94: 288: 26.41
+	Hs
		503763 HSP7C_HUMAN (2-642): 0: 937: 73.91		TERA_HUMAN (72-362): 7.75e-83: 269: 32.77
+	Sc
		491404 HSP71_YEAST (1-642): 0: 925: 100.00		TBP6_YEAST (26-361): 8.83e-48: 174: 35.33
+	Sc
		494116 HSP72_YEAST (1-642): 0: 922: 96.26		TBP6_YEAST (26-361): 8.83e-48: 174: 35.33