HitPredict

Interactor 1: HSP71 (P10591)
Heat shock protein SSA1 (Heat shock protein YG100)
Gene: SSA1

Interactor 2: PRS7 (P33299)
26S proteasome regulatory subunit 7 homolog (Protein CIM5) (Tat-binding homolog 3)
Gene: RPT1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	19412160, 29507114, 16429126
Identification Methods	pull down, affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0016887 - ATP hydrolysis activity GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 642 Sc			1 467
+	Sc
		493558 HSP72_YEAST (1-642): 0: 922: 96.26		PRS7_YEAST (1-467): 2.69e-137: 405: 100.00
+	Hs
		503623 HSP7C_HUMAN (2-642): 0: 937: 73.91		PRS6B_HUMAN (43-459): 4.68e-123: 366: 35.49
+	Hs
		66342 Q53FC7_HUMAN (4-642): 0: 937: 69.32		A8K2M0_HUMAN (43-459): 4.68e-123: 366: 35.49
+	Hs
		503823 HSP7C_HUMAN (2-642): 0: 937: 73.91		PRS8_HUMAN (81-464): 6.1e-121: 361: 44.53
+	Hs
		503834 HSP7C_HUMAN (2-642): 0: 937: 73.91		PRS10_HUMAN (81-463): 5.38e-120: 358: 42.04
+	Sc
		450155 HSP73_YEAST (1-642): 0: 925: 79.05		PRS8_YEAST (142-452): 2.32e-105: 320: 51.77
+	Sc
		492161 HSP71_YEAST (1-642): 0: 925: 100.00		PRS8_YEAST (142-452): 2.32e-105: 320: 51.77
+	Sc
		494737 HSP72_YEAST (1-642): 0: 922: 96.26		PRS8_YEAST (142-452): 2.32e-105: 320: 51.77
+	Hs
		503763 HSP7C_HUMAN (2-642): 0: 937: 73.91		TERA_HUMAN (33-442): 6.46e-80: 265: 28.13