HitPredict

Interactor 1: HSP71 (P10591)
Heat shock protein SSA1 (Heat shock protein YG100)
Gene: SSA1

Interactor 2: GCN1 (P33892)
eIF-2-alpha kinase activator GCN1 (General control non-derepressible protein 1) (Translational activator GCN1)
Gene: GCN1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	22940862, 19536198, 23217712
Identification Methods	affinity chromatography technology, tandem affinity purification, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 642 Sc			1 2672
+	Sc
		449999 HSP73_YEAST (1-642): 0: 925: 79.05		GCN1_YEAST (1-2672): 0: 1798: 100.00
+	Sc
		493588 HSP72_YEAST (1-642): 0: 922: 96.26		GCN1_YEAST (1-2672): 0: 1798: 100.00
+	Sc
		490237 HSP71_YEAST (1-642): 0: 925: 100.00		EF3A_YEAST (1321-1710): 6.99e-83: 299: 22.87
+	Hs
		503510 HSP7C_HUMAN (2-642): 0: 937: 73.91		2AAA_HUMAN (1315-1936): 3.9e-70: 250: 14.42
+	Hs
		503511 HSP7C_HUMAN (2-642): 0: 937: 73.91		2AAB_HUMAN (1663-2209): 4.74e-57: 212: 14.98
+	Sp
		223785 HSP72_SCHPO (1-642): 0: 952: 78.05		2AAA_SCHPO (1640-2239): 9.32e-33: 138: 12.92
+	Sc
		492719 HSP71_YEAST (1-642): 0: 925: 100.00		NEW1_YEAST (1361-1636): 7.06e-35: 149: 18.95
+	Sc
		495207 HSP72_YEAST (1-642): 0: 922: 96.26		NEW1_YEAST (1361-1636): 7.06e-35: 149: 18.95
+	Hs
		504227 HSP7C_HUMAN (2-642): 0: 937: 73.91		ECM29_HUMAN (1400-2598): 3.58e-14: 81.2: 10.27
+	Hs
		714005 HS71L_HUMAN (2-642): 0: 949: 72.52		CAND1_HUMAN (814-1469): 2.62e-09: 65.1: 13.54
+	Sc
		490836 HSP71_YEAST (1-642): 0: 925: 100.00		UTP20_YEAST (1367-2411): 3.05e-15: 85.2: 11.49
+	Sc
		493631 HSP72_YEAST (1-642): 0: 922: 96.26		UTP20_YEAST (1367-2411): 3.05e-15: 85.2: 11.49
+	Hs
		504341 HSP7C_HUMAN (2-642): 0: 937: 73.91		CAND1_HUMAN (814-1469): 2.62e-09: 65.1: 13.54
+	Dm
		505106 HSP7D_DROME (2-642): 0: 925: 73.15		Q9VRV9_DROME (757-1454): 1.82e-11: 72.1: 9.86