HitPredict

Interactor 1: HSP71 (P10591)
Heat shock protein SSA1 (Heat shock protein YG100)
Gene: SSA1

Interactor 2: DEF1 (P35732)
RNA polymerase II degradation factor 1 (RRM3-interacting protein 1)
Gene: DEF1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.672

Property	Details
Experiments	26217697, 25452130, 29180430, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 642 Sc			1 738
+	Sc
		605330 HSP74_YEAST (1-642): 0: 961: 81.09		DEF1_YEAST (1-738): 7.77e-65: 231: 100.00
+	Sc
		493644 HSP72_YEAST (1-642): 0: 922: 96.26		DEF1_YEAST (1-738): 7.77e-65: 231: 100.00
+	Sc
		495219 HSP72_YEAST (1-642): 0: 922: 96.26		MDN1_YEAST (34-486): 2.02e-18: 92.9: 12.26
+	Hs
		504482 HSP7C_HUMAN (2-642): 0: 937: 73.91		TITIN_HUMAN (54-668): 3.4e-13: 75.9: 8.39
+	Hs
		504250 HSP7C_HUMAN (2-642): 0: 937: 73.91		NIPBL_HUMAN (40-519): 1.26e-10: 67.4: 9.78