HitPredict

Interactor 1: HSP71 (P10591)
Heat shock protein SSA1 (Heat shock protein YG100)
Gene: SSA1

Interactor 2: UBP6 (P43593)
Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.4.19.12) (Deubiquitinating enzyme 6) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6)
Gene: UBP6

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0072671 - mitochondria-associated ubiquitin-dependent protein catabolic process
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 642 Sc			1 499
+	Sc
		494267 HSP72_YEAST (1-642): 0: 922: 96.26		UBP6_YEAST (1-495): 9.09e-119: 359: 100.00
+	Hs
		503750 HSP7C_HUMAN (2-642): 0: 937: 73.91		UBP14_HUMAN (5-499): 1.27e-103: 320: 29.12
+	Hs
		504884 HSP7C_HUMAN (2-642): 0: 937: 73.91		UBP36_HUMAN (3-496): 3.71e-76: 261: 14.46
+	Hs
		504089 HSP7C_HUMAN (2-642): 0: 937: 73.91		UBP10_HUMAN (2-499): 2.81e-76: 257: 14.18
+	Hs
		871810 HSP72_HUMAN (2-642): 0: 923: 71.05		UBP36_HUMAN (3-496): 3.71e-76: 261: 14.46
+	Hs
		503819 HSP7C_HUMAN (2-642): 0: 937: 73.91		UBP46_HUMAN (65-497): 5.21e-75: 242: 15.68
+	Hs
		504517 HSP7C_HUMAN (2-642): 0: 937: 73.91		USP9X_HUMAN (87-497): 2.59e-65: 231: 16.63
+	Mm
		883701 HSP7C_MOUSE (2-642): 0: 937: 74.07		UBP25_MOUSE (87-376): 8.4e-53: 194: 19.67
+	Hs
		713927 HS71L_HUMAN (2-642): 0: 949: 72.52		UBP11_HUMAN (325-499): 1.73e-30: 127: 18.64
+	Hs
		503718 HSP7C_HUMAN (2-642): 0: 937: 73.91		UBP11_HUMAN (325-499): 1.73e-30: 127: 18.64
+	Hs
		504837 HSP7C_HUMAN (2-642): 0: 937: 73.91		UBP40_HUMAN (110-360): 2.74e-27: 118: 18.01
+	Hs
		849965 HSP72_HUMAN (2-642): 0: 923: 71.05		UBP11_HUMAN (325-499): 1.73e-30: 127: 18.64