HitPredict

Interactor 1: HSP71 (P10591)
Heat shock protein SSA1 (Heat shock protein YG100)
Gene: SSA1

Interactor 2: CYP7 (P47103)
Peptidyl-prolyl cis-trans isomerase CYP7 (PPIase CYP7) (EC 5.2.1.8) (Rotamase CYP7)
Gene: CPR7

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.683

Property	Details
Experiments	15082786, 19536198, 18197703, 9819422
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006457 - protein folding GO:0042026 - protein refolding GO:0051082 - unfolded protein binding
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 642 Sc			1 393
+	Sc
		605366 HSP74_YEAST (1-642): 0: 961: 81.09		CYP7_YEAST (1-393): 1.52e-111: 333: 100.00
+	Ca
		804455 HSP72_CANAL (1-642): 0: 974: 85.43		PPID_CANAL (1-393): 5.28e-104: 313: 37.06
+	Hs
		503968 HSP7C_HUMAN (2-642): 0: 937: 73.91		PPID_HUMAN (3-393): 3.44e-113: 336: 30.10
+	Ca
		784139 HSP71_CANAL (1-603): 0: 946: 85.67		PPID_CANAL (1-393): 5.28e-104: 313: 37.06
+	Sc
		450095 HSP73_YEAST (1-642): 0: 925: 79.05		CYP7_YEAST (1-393): 1.52e-111: 333: 100.00
+	Sc
		494338 HSP72_YEAST (1-642): 0: 922: 96.26		CYP7_YEAST (1-393): 1.52e-111: 333: 100.00
+	Sc
		491994 HSP71_YEAST (1-642): 0: 925: 100.00		PPID_YEAST (2-393): 2.65e-95: 291: 37.88
+	Sc
		494588 HSP72_YEAST (1-642): 0: 922: 96.26		PPID_YEAST (2-393): 2.65e-95: 291: 37.88
+	Hs
		503513 HSP7C_HUMAN (2-642): 0: 937: 73.91		PPIF_HUMAN (4-198): 3.48e-72: 226: 40.31
+	Sc
		605308 HSP74_YEAST (1-642): 0: 961: 81.09		CYPC_YEAST (5-196): 4.77e-59: 191: 36.79
+	Sc
		490206 HSP71_YEAST (1-642): 0: 925: 100.00		CYPH_YEAST (6-179): 1.21e-64: 205: 41.14
+	Sc
		493093 HSP72_YEAST (1-642): 0: 922: 96.26		CYPH_YEAST (6-179): 1.21e-64: 205: 41.14
+	Sc
		449937 HSP73_YEAST (1-642): 0: 925: 79.05		CYPC_YEAST (5-196): 4.77e-59: 191: 36.79
+	Sc
		490493 HSP71_YEAST (1-642): 0: 925: 100.00		CYPC_YEAST (5-196): 4.77e-59: 191: 36.79
+	Sc
		493331 HSP72_YEAST (1-642): 0: 922: 96.26		CYPC_YEAST (5-196): 4.77e-59: 191: 36.79