HitPredict

Interactor 1: HSP71 (P10591)
Heat shock protein SSA1 (Heat shock protein YG100)
Gene: SSA1

Interactor 2: MPS1 (P54199)
Serine/threonine-protein kinase MPS1 (EC 2.7.12.2) (Monopolar spindle protein 1) (Regulatory cell proliferation kinase 1)
Gene: MPS1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	36269765, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 642 Sc			1 764
+	Sc
		494684 HSP72_YEAST (1-642): 0: 922: 96.26		MPS1_YEAST (1-764): 0: 645: 100.00
+	Hs
		503390 HSP7C_HUMAN (2-642): 0: 937: 73.91		KPCA_HUMAN (244-761): 3.47e-125: 391: 16.89
+	Hs
		503922 HSP7C_HUMAN (2-642): 0: 937: 73.91		KPCE_HUMAN (344-761): 7.36e-119: 376: 19.59
+	Mm
		554912 HS71A_MOUSE (2-642): 0: 935: 72.67		KPCE_MOUSE (342-761): 4.19e-119: 377: 18.58
+	Hs
		564016 HSP76_HUMAN (4-642): 0: 940: 69.94		AKT1_HUMAN (354-759): 1.52e-120: 372: 17.55
+	Hs
		713942 HS71L_HUMAN (2-642): 0: 949: 72.52		CDK3_HUMAN (437-732): 1.04e-118: 361: 21.63
+	Hs
		503528 HSP7C_HUMAN (2-642): 0: 937: 73.91		AKT1_HUMAN (354-759): 1.52e-120: 372: 17.55
+	Hs
		503460 HSP7C_HUMAN (2-642): 0: 937: 73.91		CDK2_HUMAN (437-722): 2.24e-121: 367: 21.68
+	Hs
		503902 HSP7C_HUMAN (2-642): 0: 937: 73.91		CDK3_HUMAN (437-732): 1.04e-118: 361: 21.63
+	Sc
		490434 HSP71_YEAST (1-642): 0: 925: 100.00		KIN82_YEAST (275-722): 8.03e-113: 360: 22.83
+	Sc
		493279 HSP72_YEAST (1-642): 0: 922: 96.26		KIN82_YEAST (275-722): 8.03e-113: 360: 22.83
+	At
		612295 HS701_ARATH (2-642): 0: 939: 71.25		CDKA1_ARATH (438-718): 3.52e-96: 302: 25.25
+	Hs
		564201 HSP76_HUMAN (4-642): 0: 940: 69.94		KS6B2_HUMAN (440-704): 1.15e-18: 91.7: 29.86
+	Hs
		504896 HSP7C_HUMAN (2-642): 0: 937: 73.91		KS6B2_HUMAN (440-704): 1.15e-18: 91.7: 29.86
+	Sc
		490665 HSP71_YEAST (1-642): 0: 925: 100.00		CDC5_YEAST (350-728): 3.61e-20: 97.4: 25.96
+	Sc
		490253 HSP71_YEAST (1-642): 0: 925: 100.00		PHO85_YEAST (436-668): 3.87e-21: 96.7: 30.71
+	Sc
		491095 HSP71_YEAST (1-642): 0: 925: 100.00		KIC1_YEAST (438-730): 9.81e-20: 96.7: 28.28
+	Sc
		493128 HSP72_YEAST (1-642): 0: 922: 96.26		PHO85_YEAST (436-668): 3.87e-21: 96.7: 30.71
+	Sc
		493865 HSP72_YEAST (1-642): 0: 922: 96.26		KIC1_YEAST (438-730): 9.81e-20: 96.7: 28.28