HitPredict

Interactor 1: HSP72 (P10592)
Heat shock protein SSA2
Gene: SSA2

Interactor 2: UBC3 (P14682)
Ubiquitin-conjugating enzyme E2-34 kDa (EC 2.3.2.23) (Cell division control protein 34) (E2 ubiquitin-conjugating enzyme 3) (E3 ubiquitin ligase complex SCF subunit CDC34) (Ubiquitin carrier protein) (Ubiquitin-protein ligase)
Gene: CDC34

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	19536198
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 639 Sc			1 295
+	Sc
		490197 HSP71_YEAST (1-639): 0: 969: 97.04		UBC3_YEAST (1-295): 6.77e-94: 281: 100.00
+	Sc
		449883 HSP73_YEAST (1-639): 0: 961: 78.89		UBC3_YEAST (1-295): 6.77e-94: 281: 100.00
+	Hs
		564035 HSP76_HUMAN (4-639): 0: 952: 70.58		UB2R1_HUMAN (13-229): 7.59e-67: 210: 33.63
+	Hs
		503677 HSP7C_HUMAN (2-639): 0: 948: 74.34		UB2R1_HUMAN (13-229): 7.59e-67: 210: 33.63
+	Sc
		493108 HSP72_YEAST (1-639): 0: 935: 100.00		UBC4_YEAST (13-168): 2.11e-69: 213: 30.13
+	Hs
		504528 HSP7C_HUMAN (2-639): 0: 948: 74.34		UB2E3_HUMAN (1-168): 6.29e-63: 199: 28.40
+	Hs
		827884 HSP72_HUMAN (2-639): 0: 933: 71.23		UB2R1_HUMAN (13-229): 7.59e-67: 210: 33.63
+	Hs
		828965 HSP72_HUMAN (2-639): 0: 933: 71.23		UBE2A_HUMAN (7-170): 3.1e-63: 198: 35.37