HitPredict

Interactor 1: HSP72 (P10592)
Heat shock protein SSA2
Gene: SSA2

Interactor 2: CYPH (P14832)
Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8) (Cyclophilin) (CPH) (Cyclosporin A-binding protein) (PPI-II) (Rotamase)
Gene: CPR1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	19536198, 16429126
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0005829 - cytosol GO:0005886 - plasma membrane and 1 others more... GO:0006457 - protein folding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 639 Sc			1 162
+	Sc
		490493 HSP71_YEAST (1-639): 0: 969: 97.04		CYPC_YEAST (3-162): 2.46e-88: 257: 71.25
+	Sc
		490206 HSP71_YEAST (1-639): 0: 969: 97.04		CYPH_YEAST (1-162): 2.94e-88: 256: 100.00
+	Sc
		449937 HSP73_YEAST (1-639): 0: 961: 78.89		CYPC_YEAST (3-162): 2.46e-88: 257: 71.25
+	Sc
		605308 HSP74_YEAST (1-639): 0: 960: 81.62		CYPC_YEAST (3-162): 2.46e-88: 257: 71.25
+	Hs
		503513 HSP7C_HUMAN (2-639): 0: 948: 74.34		PPIF_HUMAN (2-162): 1.45e-91: 266: 69.57
+	Hs
		503968 HSP7C_HUMAN (2-639): 0: 948: 74.34		PPID_HUMAN (2-162): 9.39e-87: 260: 58.58
+	Hs
		504960 HSP7C_HUMAN (2-639): 0: 948: 74.34		PPIE_HUMAN (2-161): 1.94e-87: 259: 61.25
+	Hs
		564006 HSP76_HUMAN (4-639): 0: 952: 70.58		PPIB_HUMAN (3-162): 9.69e-87: 254: 60.25
+	Hs
		503447 HSP7C_HUMAN (2-639): 0: 948: 74.34		PPIB_HUMAN (3-162): 9.69e-87: 254: 60.25
+	Sc
		493331 HSP72_YEAST (1-639): 0: 935: 100.00		CYPC_YEAST (3-162): 2.46e-88: 257: 71.25
+	Ca
		804455 HSP72_CANAL (1-639): 0: 972: 84.19		PPID_CANAL (2-162): 1.26e-64: 203: 61.14
+	Ca
		784139 HSP71_CANAL (1-603): 0: 942: 85.17		PPID_CANAL (2-162): 1.26e-64: 203: 61.14