HitPredict

Interactor 1: HSP72 (P10592)
Heat shock protein SSA2
Gene: SSA2

Interactor 2: SEC63 (P14906)
Protein translocation protein SEC63 (Protein NPL1) (Sec62/63 complex 73 kDa subunit)
Gene: SEC63

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	22940862, 16429126
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	DnaJ~HSP70
Common GO terms	GO:0005739 - mitochondrion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 639 Sc			1 663
+	Sc
		490209 HSP71_YEAST (1-639): 0: 969: 97.04		SEC63_YEAST (1-663): 0: 568: 100.00
+	Sc
		490698 HSP71_YEAST (1-639): 0: 969: 97.04		BRR2_YEAST (227-611): 2.16e-60: 221: 12.89
+	Sc
		491964 HSP71_YEAST (1-639): 0: 969: 97.04		SLH1_YEAST (222-516): 4.11e-48: 185: 10.53
+	Hs
		714084 HS71L_HUMAN (2-639): 0: 959: 72.08		DJB12_HUMAN (60-253): 1.45e-39: 151: 19.25
+	Hs
		279280 HS71L_HUMAN (2-639): 0: 959: 72.08		DNJB5_HUMAN (124-248): 3.06e-39: 149: 25.60
+	Hs
		714026 HS71L_HUMAN (2-639): 0: 959: 72.08		DJB14_HUMAN (109-255): 1.74e-37: 145: 22.97
+	Hs
		714022 HS71L_HUMAN (2-639): 0: 959: 72.08		DNJB8_HUMAN (125-244): 2.92e-38: 143: 28.33
+	Hs
		279274 HSP76_HUMAN (4-639): 0: 952: 70.58		DNJB5_HUMAN (124-248): 3.06e-39: 149: 25.60
+	Hs
		636461 HS71L_HUMAN (2-639): 0: 959: 72.08		DNJB2_HUMAN (126-241): 6.19e-36: 139: 29.51
+	Hs
		564130 HSP76_HUMAN (4-639): 0: 952: 70.58		DNJB8_HUMAN (125-244): 2.92e-38: 143: 28.33
+	Hs
		564137 HSP76_HUMAN (4-639): 0: 952: 70.58		DNJB3_HUMAN (124-240): 1.61e-38: 141: 28.21
+	Hs
		564009 HSP76_HUMAN (4-639): 0: 952: 70.58		DNJB2_HUMAN (126-241): 6.19e-36: 139: 29.51
+	Hs
		257928 HS71L_HUMAN (2-639): 0: 959: 72.08		DNJB6_HUMAN (123-195): 7.41e-29: 119: 45.21
+	Hs
		257907 HSP76_HUMAN (4-639): 0: 952: 70.58		DNJB6_HUMAN (123-195): 7.41e-29: 119: 45.21
+	Hs
		714088 HS71L_HUMAN (2-639): 0: 959: 72.08		DNJB4_HUMAN (125-198): 1.44e-26: 112: 43.24
+	Hs
		564108 HSP76_HUMAN (4-639): 0: 952: 70.58		DNJB7_HUMAN (123-206): 1.03e-27: 115: 38.10
+	Sp
		223786 HSP72_SCHPO (1-639): 0: 958: 77.74		BRR2_SCHPO (263-598): 1.01e-14: 80.4: 12.94
+	Sc
		491252 HSP71_YEAST (1-639): 0: 969: 97.04		XDJ1_YEAST (127-204): 4.78e-09: 61.2: 41.03
+	Sc
		491414 HSP71_YEAST (1-639): 0: 969: 97.04		JEM1_YEAST (125-205): 6.38e-09: 61.2: 39.77
+	Hs
		714087 HS71L_HUMAN (2-639): 0: 959: 72.08		DJB11_HUMAN (125-207): 1.38e-09: 62.4: 44.19