HitPredict

Interactor 1: HSP72 (P10592)
Heat shock protein SSA2
Gene: SSA2

Interactor 2: PHO85 (P17157)
Cyclin-dependent protein kinase PHO85 (EC 2.7.11.22) (Negative regulator of the PHO system) (Serine/threonine-protein kinase PHO85)
Gene: PHO85

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.585

Property	Details
Experiments	16319894, 16429126
Identification Methods	enzymatic study, tandem affinity purification
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 639 Sc			1 305
+	Sc
		490253 HSP71_YEAST (1-639): 0: 969: 97.04		PHO85_YEAST (1-305): 6.32e-140: 398: 100.00
+	Hs
		713942 HS71L_HUMAN (2-639): 0: 959: 72.08		CDK3_HUMAN (4-304): 1.01e-141: 403: 52.65
+	Hs
		503460 HSP7C_HUMAN (2-639): 0: 948: 74.34		CDK2_HUMAN (4-303): 7.49e-145: 410: 54.82
+	Hs
		503902 HSP7C_HUMAN (2-639): 0: 948: 74.34		CDK3_HUMAN (4-304): 1.01e-141: 403: 52.65
+	At
		612295 HS701_ARATH (2-639): 0: 952: 71.16		CDKA1_ARATH (4-300): 4.44e-136: 388: 51.17
+	Sc
		339379 HSP71_YEAST (1-639): 0: 969: 97.04		CDK1_YEAST (6-299): 5.63e-128: 368: 52.17
+	Hs
		564038 HSP76_HUMAN (4-639): 0: 952: 70.58		CDK7_HUMAN (2-304): 5.47e-126: 365: 38.76
+	Hs
		503702 HSP7C_HUMAN (2-639): 0: 948: 74.34		CDK7_HUMAN (2-304): 5.47e-126: 365: 38.76
+	Hs
		483754 HS71A_HUMAN (2-639): 0: 940: 73.01		CDK7_HUMAN (2-304): 5.47e-126: 365: 38.76
+	Sc
		339380 HSP72_YEAST (1-639): 0: 935: 100.00		CDK1_YEAST (6-299): 5.63e-128: 368: 52.17
+	Mm
		509463 HSP72_MOUSE (4-607): 0: 870: 73.40		CDK1_MOUSE (4-300): 7.81e-134: 383: 49.33