HitPredict

Interactor 1: HSP72 (P10592)
Heat shock protein SSA2
Gene: SSA2

Interactor 2: IXR1 (P33417)
Intrastrand cross-link recognition protein (Structure-specific recognition protein) (SSRP)
Gene: IXR1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	29438513, 19536198, 16429126
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 639 Sc			1 597
+	Sc
		490782 HSP71_YEAST (1-639): 0: 969: 97.04		IXR1_YEAST (1-597): 9.18e-115: 356: 100.00
+	Sc
		449993 HSP73_YEAST (1-639): 0: 961: 78.89		IXR1_YEAST (1-597): 9.18e-115: 356: 100.00
+	Sc
		605325 HSP74_YEAST (1-639): 0: 960: 81.62		IXR1_YEAST (1-597): 9.18e-115: 356: 100.00
+	Hs
		504610 HSP7C_HUMAN (2-639): 0: 948: 74.34		CIC_HUMAN (133-440): 1.99e-32: 136: 13.93
+	Hs
		871744 HSP72_HUMAN (2-639): 0: 933: 71.23		CIC_HUMAN (133-440): 1.99e-32: 136: 13.93
+	Hs
		175743 HSP7C_HUMAN (2-639): 0: 948: 74.34		HMGB3_HUMAN (296-433): 6.7e-25: 104: 15.28
+	Hs
		503969 HSP7C_HUMAN (2-639): 0: 948: 74.34		SSRP1_HUMAN (413-573): 8.74e-22: 101: 12.35
+	Hs
		449509 HSP7C_HUMAN (2-639): 0: 948: 74.34		HMGB1_HUMAN (279-440): 7.11e-23: 99: 14.12
+	Hs
		503899 HSP7C_HUMAN (2-639): 0: 948: 74.34		TFAM_HUMAN (434-580): 5.96e-17: 82.7: 19.73
+	Sc
		493030 HSP72_YEAST (1-639): 0: 935: 100.00		NHP6A_YEAST (418-503): 1.66e-18: 82.6: 27.91
+	Sc
		493031 HSP72_YEAST (1-639): 0: 935: 100.00		NHP6B_YEAST (338-433): 2.16e-18: 82.3: 25.00
+	Sc
		494747 HSP72_YEAST (1-639): 0: 935: 100.00		ABF2_YEAST (324-426): 1.38e-09: 59.7: 14.56