HitPredict

Interactor 1: HSP72 (P10592)
Heat shock protein SSA2
Gene: SSA2

Interactor 2: DEF1 (P35732)
RNA polymerase II degradation factor 1 (RRM3-interacting protein 1)
Gene: DEF1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	29180430, 19536198, 16429126
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 639 Sc			1 738
+	Sc
		490845 HSP71_YEAST (1-639): 0: 969: 97.04		DEF1_YEAST (1-738): 7.77e-65: 231: 100.00
+	Sc
		605330 HSP74_YEAST (1-639): 0: 960: 81.62		DEF1_YEAST (1-738): 7.77e-65: 231: 100.00
+	Sc
		495219 HSP72_YEAST (1-639): 0: 935: 100.00		MDN1_YEAST (34-486): 2.02e-18: 92.9: 12.26
+	Hs
		504482 HSP7C_HUMAN (2-639): 0: 948: 74.34		TITIN_HUMAN (54-668): 3.4e-13: 75.9: 8.39
+	Hs
		504250 HSP7C_HUMAN (2-639): 0: 948: 74.34		NIPBL_HUMAN (40-519): 1.26e-10: 67.4: 9.78